Comparing the Neuropsychological Test Performance of Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans with and without Blast Exposure, Mild Traumatic Brain Injury, and Posttraumatic Stress Symptoms.
Comparing the Neuropsychological Test Performance of Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans with and without Blast Exposure, Mild Traumatic Brain Injury, and Posttraumatic Stress Symptoms.
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比较持久自由行动/伊拉克自由行动 (OEF/OIF) 退伍军人在有或没有爆炸暴露、轻度创伤性脑损伤和创伤后应激症状的情况下的神经心理测试表现。
DOI：
10.1017/s1355617715000326
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
Huckans,Marilyn
中科院分区：
文献类型：
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作者：
Storzbach,Daniel;O'Neil,MayaElin;Roost,Saw-Myo;Kowalski,Halina;Iverson,GrantL;Binder,LaurenceM;Fann,JesseR;Huckans,Marilyn
比较有或没有轻度创伤性脑损伤 (MTBI)、爆炸暴露和创伤后应激障碍 (PTSD) 症状的退伍军人的神经心理学测试表现。我们将 49 名因战斗爆炸暴露而诊断为 MTBI 的持久自由行动/伊拉克自由行动 (OEF/OIF) 退伍军人与 20 名没有 MTBI 历史的爆炸暴露 OEF/OIF 退伍军人、23 名没有爆炸暴露或 MTBI 历史的 OEF/OIF 退伍军人以及 40 名匹配的平民对照者的神经心理学测试表现进行了比较。所有四个参与者组的神经心理学测试表现的比较显示出混合显着性和大多数不显着性结果的复杂模式，综合测试对于注意力、空间能力和执行功能的测量具有重要意义。最一致的模式是，有 MTBI 历史的爆炸暴露退伍军人和没有 MTBI 历史的爆炸暴露退伍军人之间不存在显着差异。当有或没有 MTBI 历史的爆炸暴露退伍军人群体被汇总并与非爆炸暴露退伍军人进行比较时，学习和记忆、空间能力和执行功能的某些指标存在显着差异。然而，PTSD 症状严重程度的协变消除了退伍军人群体之间所有显着的综合神经心理学差异。我们的结果表明，虽然一些轻微的神经认知影响与爆炸暴露有关，但这些神经认知影响可能可以通过 PTSD 症状的严重程度来更好地解释，而不是仅通过爆炸暴露或 MTBI 病史来解释。 (JINS, 2015, 21, 353–363)
To compare neuropsychological test performance of Veterans with and without mild traumatic brain injury (MTBI), blast exposure, and posttraumatic stress disorder (PTSD) symptoms. We compared the neuropsychological test performance of 49 Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans diagnosed with MTBI resulting from combat blast-exposure to that of 20 blast-exposed OEF/OIF Veterans without history of MTBI, 23 OEF/OIF Veterans with no blast exposure or MTBI history, and 40 matched civilian controls. Comparison of neuropsychological test performance across all four participant groups showed a complex pattern of mixed significant and mostly nonsignificant results, with omnibus tests significant for measures of attention, spatial abilities, and executive function. The most consistent pattern was the absence of significant differences between blast-exposed Veterans with MTBI history and blast-exposed Veterans without MTBI history. When blast-exposed Veteran groups with and without MTBI history were aggregated and compared to non–blast-exposed Veterans, there were significant differences for some measures of learning and memory, spatial abilities, and executive function. However, covariation for severity of PTSD symptoms eliminated all significant omnibus neuropsychological differences between Veteran groups. Our results suggest that, although some mild neurocognitive effects were associated with blast exposure, these neurocognitive effects might be better explained by PTSD symptom severity rather than blast exposure or MTBI history alone. (JINS, 2015, 21, 353–363)