Molecularly imprinted solid phase extraction for detection of Sudan I in food matrices
Molecularly imprinted solid phase extraction for detection of Sudan I in food matrices
复制标题
DOI：
10.1016/j.foodchem.2004.11.014
复制
发表时间：
2005-11-01
期刊：
影响因子：
8.8
通讯作者：
Picci, N
中科院分区：
文献类型：
--
作者：
Puoci, F;Garreffa, C;Picci, N
苏丹红I是一种合成偶氮染料。作为食品添加剂，特别是含有辣椒粉的食品，因为他强烈的红橙色。由于苏丹红一号具有致癌性，欧盟已禁止其作为食品添加剂。开发了几种方法来检测该化合物的存在（HPLC，GC/MS）。然而，当“苏丹红P”仅在食品中痕量混合时，需要非常昂贵的仪器（LC/MS/MS）来揭示它。该程序允许浓缩该化合物以使其可通过HPLC检测。此外，我们研究了这些MISPE药筒从食品基质中选择性吸收苏丹红I的能力。与非印迹聚合物（NIPS）相比，印迹聚合物作为固相萃取固定相时，与苏丹红P的相互作用有很大的不同。2004爱思唯尔有限公司保留所有权利。
Sudan I is a synthetic azoic dye employed. as an additive in foods, and in particularly in those containing chilli powders, because of his intense red-orange colour. Now European Community does not allow "Sudan I" as an additive in foods because of its demonstrated cancerogenity. Several methods were developed to detect the presence of this compound (HPLC, GC/MS). However when "Sudan P is mixed just in traces in foods; very expensive instruments are necessary (LC/MS/MS) to reveal it. This study describes the synthesis of a molecularly imprinted polymers (MIPs) for solid phase extraction (MISPE) using Sudan I as template. This procedure allows to concentrate this compound in order to make it detectable by HPLC. Furthermore we investigated the ability of these MISPE cartridges to absorb selectively Sudan I from food matrices. Considerable differences in the interaction with "Sudan P were observed when MIPs were used as stationary phase in SPE compared with the non imprinted polymers (NIPS). 2004 Elsevier Ltd. All rights reserved.