LACK OF CORRELATION BETWEEN CADMIUM IN SEMINAL PLASMA AND FERTILITY STATUS OF NONEXPOSED INDIVIDUALS AND 2 CADMIUM-EXPOSED PATIENTS
LACK OF CORRELATION BETWEEN CADMIUM IN SEMINAL PLASMA AND FERTILITY STATUS OF NONEXPOSED INDIVIDUALS AND 2 CADMIUM-EXPOSED PATIENTS
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DOI：
10.1016/0890-6238(94)00053-y
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发表时间：
1995-01-01
影响因子：
3.3
通讯作者：
NIESCHLAG, E
中科院分区：
文献类型：
--
作者：
KECK, C;BRAMKAMP, G;NIESCHLAG, E
测定了12例确诊有生育能力的男性(第I组)、44例正常精子症患者(第II组)、118例不育症门诊患者(第III组)和2名职业接触镉的产业工人精液中镉的浓度。精浆镉浓度在第I组、第II组和第III组之间无显著差异：0.38±0.64；0.44+/-0.73(均值+/-SD，Mu g/L)，但两组镉暴露患者的精镉水平分别为3.46 mU/L和2.99 mU/L。精镉水平与精液常规参数及生育状况均无相关性，而正常精子症患者精浆平均镉水平高于吸烟组(0.55+/-0.81 mU/L)。与非吸烟组(0.42+/-0.67ug/L)相比，镉浓度与日吸烟量之间的相关性较弱。
Cadmium concentrations were determined in semen samples of 12 men with proven fertility (group I) and 44 normozoospermic patients (group II) as well as 118 unselected patients of an infertility clinic (group III) and 2 industrial workers with occupational exposure to cadmium, Mean cadmium concentrations in seminal plasma for groups I, II, and III did not show significant differences: 0.38 +/- 0.64; 0.43 +/- 0.69; 0.44 +/- 0.73 (mean +/- SD, mu g/L), but the two cadmium-exposed patients revealed exceptionally high cadmium levels: 3.46 mu g/L and 2.99 mu g/L, respectively, There was no significant correlation between seminal cadmium concentrations and conventional semen parameters or between cadmium concentration and the fertility status of the patients, However, mean cadmium concentrations in seminal plasma of normozoospermic patients were higher in the group of smokers (0.55 +/- 0.81 mu g/L), compared with the group of nonsmokers (0.42 +/- 0.67 mu g/L), and there was a weak correlation between cadmium concentration and number of cigarettes consumed per day.