Risk of non-fatal suicide ideation and behaviour in recent onset schizophrenia
Risk of non-fatal suicide ideation and behaviour in recent onset schizophrenia
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近期发病的精神分裂症患者非致命性自杀意念和行为的风险
DOI：
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发表时间：
2004
影响因子：
4.4
通讯作者：
L. Gregg
中科院分区：
文献类型：
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作者：
N. Tarrier;C. Barrowclough;B. Andrews;L. Gregg
摘要：背景：精神分裂症患者的自杀率很高。有缺点，在调查成功完成的自杀，使自杀意念和以前的尝试自杀风险的重要代理措施。本研究的目的是调查与这些风险measurements.Method：59例近期发病的精神分裂症患者进行了评估自杀意念和历史，以及一系列的人口统计学，临床，社会（包括亲属的表达情感）和自尊措施。单因素比较有和没有自杀意念和以前的企图。进行路径分析，以确定直接或间接相关的因素与复合规模的风险（低，中，高）。结果：约25%的样本报告说，目前的愿望，杀死自己和47%的一个或多个以前的尝试。有或没有意念或历史之间有许多显着的单变量差异。路径分析显示，更大的绝望感（OR 1.22）和更长的患病时间（OR 1.13）增加了风险。绝望与更高的负面自我评价和社会孤立有关。消极的自我评价与较多的亲属批评相关，亲属批评与较多的阴性症状相关。男性、未婚和失业都与阴性症状的增加显著相关。社会孤立与失业、年龄较大、阳性症状较多和患病时间较长有关。疾病的持续时间本身没有预测任何其他variables.Conclusion：非致命性自杀意念和行为显着相关的一系列人口，临床，人际和心理因素。为了降低自杀的风险，需要评估这些因素，并制定减少其影响的方法。
Abstract.Background:Suicide rates amongst schizophrenic patients are high. There are disadvantages in investigating successfully completed suicides which make suicidal ideation and previous attempts important proxy measures of suicidal risk. The aim of this study was to investigate factors associated with these risk measures.Method:Fifty-nine patients suffering recent onset schizophrenia were assessed for suicidal ideation and history, and a range of demographic, clinical, social (including relatives’ Expressed Emotion) and self-esteem measures. Univariate comparisons were made between those with and without suicide ideation and previous attempts. Path analysis was conducted to identify factors directly or indirectly associated with a composite scale of risk (low, medium or high).Results:Approximately 25% of the sample reported a current desire to kill themselves and 47% had made one or more previous attempts. There were numerous significant univariate differences between those with or without ideation or history. Path analysis indicated that greater hopelessness (OR 1.22) and longer duration of illness (OR 1.13) increased risk. Hopelessness was associated with higher negative self-evaluation and social isolation. Negative self-evaluation was associated with more relatives’ criticism which was associated with more negative symptoms. Being a male, unmarried and unemployed were all significantly associated with an increase in negative symptoms. Social isolation was associated with being unemployed, older, more positive symptoms and longer illness duration. Duration of illness was not itself predicted by any other variables.Conclusion:Non-fatal suicide ideation and behaviour are significantly associated with an array of demographic, clinical, interpersonal and psychological factors. To reduce risk of suicide, these factors need to be assessed and methods developed to reduce their influence.