Assays and Utilization of Enzymes Involved in Glycolipid Metabolism in Bacteria and Fungi
Assays and Utilization of Enzymes Involved in Glycolipid Metabolism in Bacteria and Fungi
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细菌和真菌中糖脂代谢相关酶的测定和利用
DOI：
10.1007/978-1-0716-2910-9_18
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发表时间：
2023
影响因子：
--
通讯作者：
Okino Nozomu
中科院分区：
文献类型：
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作者：
Ito Makoto;Ishibashi Yohei;Watanabe Takashi;Iwaki Jun;Kurita Toyohisa;Okino Nozomu
微生物鞘糖脂(GSL)降解酶具有独特的专一性，是研究GSL的有用工具。另一方面，一些微生物糖脂不仅与GSLS密切相关，而且还与甾体糖苷密切相关，因此，微生物糖脂的代谢作为抗生素的靶标引起了人们的关注。本章描述了对糖脂研究有用的微生物酶的分析和利用，以及那些涉及致病性或宿主免疫反应的微生物酶。
Microbial glycosphingolipid (GSL)-degrading enzymes with unique specificity are useful tools for GSL research. On the other hand, some microbial glycolipids, not only GSLs but also steryl glucosides, are closely related to pathogenicity, and, thus, the metabolism of microbial glycolipids is attracting attention as a target for antibiotics. This chapter describes the assays and utilization of microbial enzymes useful for glycolipid research and those involved in pathogenicity or host immune reactions.