Immunity to tuberculosis
Immunity to tuberculosis
复制标题
DOI：
10.1001/archinte.1928.00130150043002
复制
发表时间：
1928-03-01
影响因子：
--
通讯作者：
Heimbeck, J
中科院分区：
文献类型：
--
作者：
Heimbeck, J
在奥斯陆进入护士培训学校的妇女中，约有50%的人出现了阴性Pirquet反应，尽管奥斯陆约85%的9岁儿童呈阳性。在农村地区，学生中的积极反应人数较少，但进入培训学校的护士大多来自城市。在进入奥斯陆医院之前的医科学生和新兵在大约50%的检查病例中也对Pirquet试验呈阴性。作者认为成人中高比例的阴性Pirquet反应是由于青少年感染的愈合。在1-2年的时间里。“在培训学校接触肺结核病例后，护士中的消极皮凯反应变成了积极的。作者给23名Pirquet试验阴性的护士中的12名注射了0.05 mgm。的B。C. G.皮下注射未观察到不良反应; Pirquet反应变为阳性。在接下来的几个月里，4名未接种疫苗的护士感染了结核病，但12名接种了B的护士中没有一人感染。C. G.
About 50% of the women entering the nurses'' training school in Oslo gave negative Pirquet reactions, although about 85% of children in Oslo at the age of 9 were positive. In country districts the number of positive reactions among school children was less, but most of the nurses entering the training school came from the city. Medical students prior to entering the hospital at Oslo and military recruits were also negative to the Pirquet test in about 50% of the cases examined. The author assumes that the high percentage of negative Pirquet reactions among adults is due to healing of juvenile infection. In the course of 1-2 yrs.'' contact with cases of tuberculosis at the training school, negative Pirquet reactions among nurses became positive. The author injected 12 out of 23 nurses who were negative to the Pirquet test with 0.05 mgm. of B. C. G. subcutaneously. No untoward effect was noticed; the Pirquet reaction became positive. In the following few months, 4 of the unvaccinated nurses contracted tuberculosis, but none of the 12 inoculated with B. C. G.