Decreased L-arginine-nitric oxide pathway in cultured myoblasts from spontaneously hypertensive versus normotensive Wistar-Kyoto rats
Decreased L-arginine-nitric oxide pathway in cultured myoblasts from spontaneously hypertensive versus normotensive Wistar-Kyoto rats
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DOI：
10.1016/0014-5793(96)00817-4
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发表时间：
1996-09-02
期刊：
影响因子：
3.5
通讯作者：
Dubois, G
中科院分区：
文献类型：
--
作者：
Dubois, G
The hypertrophy of the arterial media exhibited by spontaneously hypertensive rats is related to the hyperproliferation of their smooth muscle cells in culture, Using two methods to assay nitric oxide synthase activity, we showed that this abnormal proliferation results from a decreased activity of the inducible NOS II and less modulation of this enzymatic activity by these cells compared to control Wistar Kyoto cells.
