Optical coherence tomography findings in stage 4A retinopathy of prematurity - A theory for visual variability
Optical coherence tomography findings in stage 4A retinopathy of prematurity - A theory for visual variability
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DOI：
10.1016/j.ophtha.2006.01.007
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发表时间：
2006-04-01
期刊：
影响因子：
13.7
通讯作者：
Capone, A
中科院分区：
文献类型：
--
作者：
Joshi, MM;Trese, MT;Capone, A
目的：报道4A期早产儿视网膜病变（ROP）患者的黄斑解剖异常，这种异常可能导致视力不佳，尽管验光镜下后极看起来正常。设计：回顾性病例系列。受试者：9例（14只眼）。方法：对9例（14眼）诊断为4A期视网膜脱离的患者行光学相干断层扫描（OCT），然后行保留晶状体的玻璃体切割修复术。1例（2只眼）患者因4A期脱离伴视力下降而成功行保留晶状体玻璃体切除术2年后接受荧光素血管造影、眼底摄影和oct成像。主要观察指标：光学相干断层扫描结果。结果：术前OCT证实14眼中12眼黄斑未受累。两只眼显示弥漫性视网膜后极改变。2岁婴儿的双眼OCT扫描显示缺乏正常的中央凹结构，血管造影显示中央凹无血管区。结论：解剖性黄斑异常（镜下不明显）可能解释了4A期ROP保留晶状体玻璃体切除术后视力结果的差异。
Purpose: To report macular anatomic abnormalities in eyes with stage 4A retinopathy of prematurity (ROP) that may account for poor visual outcome despite an ophthalmoscopically normal-appearing posterior pole.Design: Retrospective case series.Participants: Nine patients (14 eyes).Methods: Nine patients (14 eyes) diagnosed with stage 4A retinal detachments were imaged with optical coherence tomography (OCT) before repair by lens-sparing pars plana vitrectomy. One patient (2 eyes) 2 years after successful lens-sparing vitrectomy for stage 4A detachment with reduced visual acuity underwent fluorescein angiography, fundus photography, and imaging with OCT.Main Outcome Measure: Optical coherence tomography findings.Results: Preoperative OCT confirmed absence of macular involvement in 12 of 14 eyes. Two eyes demonstrated diffuse intraretinal posterior pole changes. Both eyes of a 2-year-old infant demonstrated a lack of normal foveal architecture on OCT scanning and an absent foveal avascular zone on angiography.Conclusions: Anatomic macular abnormalities-not immediately apparent ophthalmoscopically-may explain the variability in visual outcome after lens-sparing vitrectomy for stage 4A ROP.