Extensive multifocal emphysematous osteomyelitis of spine: A rare case and a review of literature.
Extensive multifocal emphysematous osteomyelitis of spine: A rare case and a review of literature.
复制标题
脊柱广泛性多灶性肺气肿性骨髓炎：罕见病例及文献综述。
DOI：
10.2174/1871526522666220614163310
复制
发表时间：
2022
期刊：
影响因子：
--
通讯作者：
A. Angrup
中科院分区：
文献类型：
--
作者：
Bhawna Sharma;V. Lakhanpal;Anuj Kumar Goyal;R. Shree;Shashank Raj;Priya Sreenivasan;M. Biswal;P. Ray;A. Angrup
背景
肺气肿性骨髓炎（EO）是一种极其罕见的骨髓炎，其主要并发于产气微生物感染。该病的常见病原体主要是肠杆菌科，最常见的是大肠埃希菌和肺炎克雷伯菌沿着厌氧菌。到目前为止，全球文献中共报告了48例EO病例，没有记录分离出无菌棒状杆菌。
个案列报
我们报告一例罕见的脊柱和骨盆气肿性骨髓炎的病例，由于大肠杆菌沿着分离出棒状杆菌amycolatum从相同的脓液样本在连续两个场合在一个50岁的女性与控制糖尿病，谁是连续治疗抗生素和引流脓。我们也做了一个简短的回顾性文献的所有病例报告到目前为止。
结论
在肺气肿性骨髓炎的病因学中，棒状杆菌的作用需要在未来的研究中进一步评估，因为我们不能完全忽视它在两个连续的样本中的分离，仅仅是一种污染物。
BACKGROUND
Emphysematous osteomyelitis (EO) is an extremely rare form of osteomyelitis which is complicated mainly by infection with gas-forming organisms. The common causative agents of this disease are mainly members of Enterobacteriaceae family, the most common are Escherichia coli and Klebsiella pneu¬moniae along with anaerobes. A total of 48 cases of EO have been reported in the literature till now globally and none have documented the isolation of Corynebacterium amycolatum.
CASE PRESENTATION
We report a rare case of emphysematous osteomyelitis of the spine and pelvis due to Escherichia coli along with the isolation of Corynebacterium amycolatum from the same pus samples in two consecutive occasions in a 50-year-old female with uncontrolled diabetes mellitus, who was successively treated with antibiotics and drainage of pus. We also did a brief review of the literature of all cases reported till now.
CONCLUSION
The role of Corynebacterium amycolatum in the etiology of emphysematous osteomyelitis needs to be evaluated further in future studies as we cannot completely ignore its isolation in two consecutive samples as a mere contaminant.