Cerebral Hemodynamic Changes and Pain Perception During Venipuncture Is Glucose Really Effective?
Cerebral Hemodynamic Changes and Pain Perception During Venipuncture Is Glucose Really Effective?
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DOI：
10.1177/0883073813511149
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发表时间：
2014-05-01
影响因子：
1.9
通讯作者：
Atalay, Yildiz
中科院分区：
文献类型：
--
作者：
Beken, Serdar;Hirfanoglu, Ibrahim Murat;Atalay, Yildiz
新生儿会受到相当多的痛苦刺激。本研究旨在探讨30%葡萄糖溶液和非营养性吸吮对静脉穿刺过程中痛觉的影响。25名足月婴儿被随机分为30%葡萄糖组（第1组）和无菌水组（第2组）。在手术过程中记录新生儿疼痛量表评分、皮肤电导痛觉计记录和近红外光谱测量。新生儿疼痛量表和皮肤电导痛觉测定仪结果在两组中从静脉穿刺期间到手术后均降低。静脉穿刺后，第1组新生儿疼痛量表评分低于第2组，与皮肤电导痛觉计不同，两组之间没有观察到差异。第1组静脉穿刺后脑血容量增加。葡萄糖不会减弱静脉穿刺过程中的新生儿疼痛量表评分和皮肤电导痛觉指数，但它会导致静脉穿刺后新生儿疼痛量表评分降低，这与皮肤电导痛觉指数不同，皮肤电导痛觉指数没有降低。
Newborns are exposed to a considerable number of painful stimuli. This study is aimed to investigate the effects of 30% glucose solution and nonnutritive sucking on pain perception during venipuncture. Twenty-five term infants were randomized as receiving 30% dextrose (group 1) or sterile water (group 2). Neonatal Infant Pain Scale scores, skin conductance algesimeter recordings, and near-infrared spectroscopy measurements were recorded during the procedure. Neonatal Infant Pain Scale and skin conductance algesimeter results were decreased in both groups from that during venipuncture to after the procedure. Group 1 had lower Neonatal Infant Pain Scale scores compared with group 2 after venipuncture, different from the skin conductance algesimeter, where no difference was observed between groups. In group 1, cerebral blood volume increased after venipuncture. Glucose does not attenuate the Neonatal Infant Pain Scale score and skin conductance algesimeter index during venipuncture, but it leads to a lower Neonatal Infant Pain Scale score after venipuncture unlike the skin conductance algesimeter index, which was not lowered.