The Purkinje cell; 2008 style.
The Purkinje cell; 2008 style.
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DOI:
10.1016/j.yjmcc.2008.08.001
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发表时间:
2008-11
影响因子:
5
通讯作者:
Boyden, Penelope A.
中科院分区:
文献类型:
--
作者:
Dun, Wen;Boyden, Penelope A.
Cardiac Purkinje fibers, due to their unique anatomical location, cell structure and electrophysiologic characteristics, play an important role in cardiac conduction and arrhythmogenesis. Purkinje cell action potentials are longer than their ventricular counterpart, and display two levels of resting potential. Purkinje cells provide for rapid propagation of the cardiac impulse to ventricular cells and have pacemaker and triggered activity, which differs from ventricular cells. Additionally, a unique intracellular Ca2+ release coordination has been revealed recently for the normal Purkinje cell. However, since the isolation of single Purkinje cells is difficult, particularly in small animals, research using Purkinje cells has been restricted. This review concentrates on comparison of Purkinje and ventricular cells in the morphology of the action potential, ionic channel function and molecular determinants by summarizing our present day knowledge of Purkinje cells.
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DOI:
10.1085/jgp.70.6.725
发表时间:
1977-12
期刊:
The Journal of general physiology
影响因子:
--
作者:
Gadsby DC;Cranefield PF
通讯作者:
Cranefield PF
影响因子:
5.5
作者:
Gaborit, Nathalie;Le Bouter, Sabrina;Demolombe, Sophie
通讯作者:
Demolombe, Sophie
影响因子:
4.5
作者:
ATTWELL, D;COHEN, I;OJEDA, C
通讯作者:
OJEDA, C
影响因子:
2.4
作者:
Desplantez, Thomas;Dupont, Emmanuel;Weingart, Robert
通讯作者:
Weingart, Robert
影响因子:
10.8
作者:
Bendahhou, S;Marionneau, C;Barhanin, J
通讯作者:
Barhanin, J