Models wagging the dog: are circuits constructed with disparate parameters?

Models wagging the dog: are circuits constructed with disparate parameters?
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模型摇狗:电路是用不同的参数构建的吗?

DOI:
10.1162/neco.2007.19.8.1985
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发表时间:
2007
期刊:
影响因子:
2.9
通讯作者:
Selverston,AllenI
Selverston,AllenI
中科院分区:
计算机科学4区
文献类型:
--
作者:
Nowotny,Thomas;Szucs,Attila;Levi,Rafael;Selverston,AllenI

文献摘要

相似文献

在最近的一篇文章中,Prinz、布赫和Marder(2004)提出了一个基本问题,即神经系统是用严格控制参数的固定蓝图构建的,还是用数据库建模方法构建的,在这种方式下,属性在个体之间会有很大的差异。在这里,我们研究的主要结论是,神经回路确实是建立在很大程度上不同的参数,根据我们自己的实验和建模观察。我们批判性地讨论了实验和理论证据,包括这种问题的数据库方法的一般充分性,并得出结论,这个基本问题的最后一句话还没有说。
In a recent article, Prinz, Bucher, and Marder (2004) addressed the fundamental question of whether neural systems are built with a fixed blueprint of tightly controlled parameters or in a way in which properties can vary largely from one individual to another, using a database modeling approach. Here, we examine the main conclusion that neural circuits indeed are built with largely varying parameters in the light of our own experimental and modeling observations. We critically discuss the experimental and theoretical evidence, including the general adequacy of database approaches for questions of this kind, and come to the conclusion that the last word for this fundamental question has not yet been spoken.