The impact of injecting drug use status on hepatitis C-related referral and treatment

The impact of injecting drug use status on hepatitis C-related referral and treatment
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DOI:
10.1016/j.drugalcdep.2004.07.002
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发表时间:
2005-01-07
影响因子:
4.2
通讯作者:
Dore, GJ
Dore, GJ
中科院分区:
医学2区
文献类型:
--
作者:
Stoové, MA;Gifford, SM;Dore, GJ

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然而,澳大利亚有超过16万人患有慢性丙型肝炎病毒(HCV)感染。医疗率很低。本研究的目的是检查以社区为基础的样本人群与HCV相关的卫生保健服务的摄取和预测因素。自填式问卷完成了一个很大程度上非临床样本的362名妇女和308名男子与丙型肝炎病毒生活在维多利亚州。根据注射吸毒(IDU)状态进行分析:无注射史(非IDU)。既往注射史(既往IDUs)和当前(过去12个月内)注射史(当前IDUs)。还评估了转诊到专科肝病诊所的双变量和多变量预测因素。51%的参与者是目前的注射吸毒者。33%的注射吸毒者和16%的非注射吸毒者。52%的女性和37%的男性报告曾被转介到专科肝病诊所,18%的女性和20%的男性报告既往接受过HCV抗病毒治疗。虽然有许多因素与转诊的可能性增加有关(例如,女性,自诊断以来的时间较长。诊断时的咨询时间更长。出现HCV相关症状)。多变量分析显示,目前不是注射吸毒者和看过专门针对HCV的GP是转诊的最重要的独立预测因素。对于那些被转诊到肝脏诊所的人,IDU病史与接受抗病毒治疗的机会较低相关。IDU状态与转诊和治疗有关。HCV治疗服务的扩展,包括全科医生和药物和酒精从业者应探讨作为模型,以改善获得抗病毒治疗。(C)2004爱思唯尔爱尔兰有限公司保留所有权利。
More than 160,000 people are living with chronic hepatitis C virus (HCV) infection in Australia, however. rates of medical treatment are low. The aim of this study is to examine uptake and predictors of HCV-related health care services among a community-based sample of people with HCV. A self-administered questionnaire was completed by a largely non-clinical sample of 362 women and 308 men with HCV living in the state of Victoria. Analyses were performed according to injecting drug use (IDU) status: no history of injecting (non-IDUs). previous history of injecting (past-IDUs) and current (within the last 12 months) history of injecting (current IDUs). Bivariate and multivariate predictors of referral to a specialist liver clinic were also assessed. Fifty-one percent of participants were current IDUs. 33% past-IDUs and 16% non-IDUs. Fifty-two percent of women and 37% of men reported ever being referred to a specialist liver clinic and 18% of women and 20% of men reported previous HCV antiviral therapy. Although there were many factors related to an increased likelihood of referral (e.g. being female, longer time since diagnosis. longer consultation time at diagnosis. experiencing HCV-related symptoms). multivariate analysis revealed that not being a current IDU and seeing a GP specifically for HCV were the most important independent predictors of referral. For those who had been referred to a liver clinic, a history of IDU was associated with a lower chance of receiving antiviral therapy. IDU status is associated with both referral and treatment. The extension of HCV treatment services to involve GPs and drug and alcohol practitioners should be explored as models to improve access to antiviral therapy. (C) 2004 Elsevier Ireland Ltd. All rights reserved.