Effects of lung volume and O2 and CO2 content on cutaneous gas exchange in frogs.
Effects of lung volume and O2 and CO2 content on cutaneous gas exchange in frogs.
复制标题
肺容量以及 O2 和 CO2 含量对青蛙皮肤气体交换的影响。
DOI：
10.1152/ajpregu.1986.251.5.r941
复制
发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Hlastala,MP
中科院分区：
文献类型：
--
作者：
Malvin,GM;Hlastala,MP
The effects of lung O2 and CO2 content and volume on cutaneous gas exchange and perfusion were investigated in the frog, Rana pipiens. (Ha)-anesthetized frogs were equilibrated with 9.5% Freon-22 (Fr, chlorodifluoromethane) and 1.1% Ha. Cutaneous elimination of Fr, Ha, and CO2 into a small sample chamber on the abdomen was measured with a mass spectrometer. Introducing an air mixture into the lung decreased cutaneous Fr, Ha, and CO2 elimination. Lung inflation with an O2 mixture decreased cutaneous gas elimination more than with the air mixture. Inflation with a N2 mixture had no effect. The response to lung inflation with the air mixture was not affected by adding 4.8% CO2 to the air mixture or by atropine. Voluntary lung ventilation decreased CO2 and Fr elimination. The results indicate that intrapulmonary O2 is a factor regulating skin breathing. If a change in lung volume is also a factor, it requires a concomitant change in lung O2. Intrapulmonary CO2 and cholinergic nerves are not involved in cutaneous respiration across the abdomen.
