Associations between daily cause-specific mortality and concentrations of ground-level ozone in Montreal, Quebec

Associations between daily cause-specific mortality and concentrations of ground-level ozone in Montreal, Quebec
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DOI:
10.1093/aje/154.9.817
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发表时间:
2001-11-01
影响因子:
5
通讯作者:
Vincent, R
Vincent, R
中科院分区:
医学2区
文献类型:
--
作者:
Goldberg, MS;Burnett, RT;Vincent, R

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作者调查了臭氧的日常变化与特定原因死亡率之间的关系。位于魁北克蒙特利尔的固定空气污染监测仪提供了臭氧、颗粒和其他气态污染物的日平均水平。获得了1984年至1993年期间在该市死亡的蒙特利尔居民的死亡日期和根本原因的资料。在考虑了死亡率时间序列的季节性和亚季节性波动、非泊松离散和天气变量后,作者对臭氧平均水平的每日死因特异性死亡率计数的对数进行了回归。臭氧对死亡率的影响在温暖季节和65岁或以上的人群中普遍较高。当3天运行平均臭氧浓度为21.3马克/米(3)时,暖季日死亡增加百分比如下:非意外死亡3.3%(95%可信区间(Cl): 1.7, 5.0);癌症,3.9% (95% Cl: 1.0, 6.91);心血管疾病,2.5% (95% Cl: 0.2, 5.0);呼吸系统疾病,6.6% (95% Cl: 1.8, 11.8)。这些结果与其他污染物的影响无关,并且与对数线性响应函数一致。
The authors investigated the association between daily variations in ozone and cause-specific mortality. Fixed-site air pollution monitors in Montreal, Quebec, provided daily mean levels of ozone, particles, and other gaseous pollutants. Information on the date and underlying cause of death was obtained for residents of Montreal who died in the city between 1984 and 1993. The authors regressed the logarithm of daily counts of cause-specific mortality on mean levels of ozone, after accounting for seasonal and subseasonal fluctuations in the mortality time series, non-Poisson dispersion, and weather variables. The effect of ozone on mortality was generally higher in the warm season and among persons aged 65 years or over. For an increase in the 3-day running mean concentration of ozone of 21.3 mug /m(3), the percentage of increase in daily deaths in the warm season was the following: nonaccidental deaths, 3.3% (95% confidence interval (Cl): 1.7, 5.0); cancer, 3.9% (95% Cl: 1.0, 6.91); cardiovascular diseases, 2.5% (95% Cl: 0.2, 5.0); and respiratory diseases, 6.6% (95% Cl: 1.8, 11.8). These results were independent of the effects of other pollutants and were consistent with a log-linear response function.