Elevated risk of adverse obstetric outcomes in pregnant women with depression.

Elevated risk of adverse obstetric outcomes in pregnant women with depression.
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DOI:
10.1007/s00737-013-0371-x
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发表时间:
2013-12
影响因子:
4.5
通讯作者:
Epperson, C. Neill
Epperson, C. Neill
中科院分区:
医学2区
文献类型:
--
作者:
Kim, Deborah R.;Sockol, Laura E.;Sammel, Mary D.;Kelly, Caroline;Moseley, Marian;Epperson, C. Neill

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In this study, we evaluated the association between patient depression ratings at an initial obstetrics visit and adverse birth outcomes in African-American women. We conducted a retrospective cohort study of 261 pregnant, African American women who were screened with the Edinburgh Postnatal Depression Scale (EPDS) at their initial prenatal visit. Medical records were reviewed to assess pregnancy and neonatal outcomes, specifically pre-eclampsia, preterm birth, intrauterine growth retardation and low birth weight. Using multivariable logistic regression models, an EPDS score ≥ 10 was associated with increased risk for preeclampsia, preterm birth and low birth weight. An EPDS score ≥ 10 was associated with increased risk for intrauterine growth retardation but after controlling for behavioral risk factors this association was no longer significant. A positive, patient-rated depression screening at the initial obstetrics visit depression is associated with increased risk for multiple adverse birth outcomes. Given the retrospective study design and small sample size, this finding should be confirmed in a prospective cohort study.
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