Clinical studies of drug addiction - Physical dependence, withdrawal and recovery
Clinical studies of drug addiction - Physical dependence, withdrawal and recovery
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DOI：
10.1001/archinte.1942.00200170048004
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发表时间：
1942-05-01
影响因子：
--
通讯作者：
Himmelsbach, CK
中科院分区：
文献类型：
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作者：
Himmelsbach, CK
体重，卡路里摄入，睡眠，B.M.R.，温度，本文对21例阿片类药物依赖者的呼吸、血压、血糖、无机磷、乳酸、血沉、红细胞压积和血细胞比容进行了研究。完全的禁欲恢复（通过这些因素的值的平稳来判断）从1周开始变化。到6个月。最大的物理恢复达到时，重量没有显着的增益。连续3个月发生。完全的禁欲恢复与成瘾数据的比较表明，调整身体功能的吗啡成瘾，而生物学上是足够的，是不完整的。只有B.M.R.和血糖在成瘾期间和恢复后相同。B.M.R.低于正常水平
Weight, caloric intake, sleep, B.M.R., temp., respiration, blood pressure, and blood glucose, inorganic P, lactic acid, sedimentation, hematocrit, and sp. gr. were studied on 21 addicts while still physically dependent on an opiate, for the first 15 days after abrupt withdrawal, and at monthly intervals to the 9th mo. of total abstinence. Recovery (as judged by a leveling-off of the values for these factors) varied from 1 wk. to 6 mos. Maximum physical recovery was reached when no significant gain in wt. occurred for 3 successive mos. of total abstinence. Comparison of the recovery with the addiction data indicated that adjustment of physical functions to morphine addiction, while biologically adequate, is not complete. Only the B.M.R. and blood sugar were the same during addiction and after recovery. The B.M.R. was subnormal.