Elevated Adenomatous Polyp Detection Rate Among Alaska Native and American Indian People in Interior Alaska, 2018-2022.
Elevated Adenomatous Polyp Detection Rate Among Alaska Native and American Indian People in Interior Alaska, 2018-2022.
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2018-2022 年阿拉斯加内陆地区的阿拉斯加原住民和美洲印第安人腺瘤性息肉检出率升高。
DOI：
10.1177/00333549221143204
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
Gerrish,StephenS
中科院分区：
文献类型：
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作者：
Redwood,DianaG;Prewitt,JenniferJ;Holt,MikailaC;Gerrish,StephenS
在美国，阿拉斯加原住民的结直肠癌（CRC）发病率和死亡率是非西班牙裔白色人的两倍;因此，结肠镜检查是阿拉斯加原住民的推荐筛查试验。腺瘤检出率（ADR）是在接受初始筛查结肠镜检查的平均CRC风险患者中测量的，反映了筛查人群中癌前息肉的患病率。我们评估了ADR阿拉斯加原住民生活在Interior Alaska.MethodsThis项目评估了ADR阿拉斯加原住民和美国印第安人年龄≥40岁（N = 460）生活在阿拉斯加内陆，使用回顾性病历审查的患者转介筛查结肠镜检查从2018年2月1日，通过2022年3月31日。主要结果的措施是ADR，分层的年龄和sex.ResultsThe ADR是45.0%的整体：43.0%的女性和47.1%的男性。在≥50岁的患者中，ADR为67.1%：女性为62.7%，男性为70.7%。在40-49岁的患者中，ADR为34.4%：女性为35.3%，男性为33.3%.ConclusionsMeasured ADR是高阿拉斯加土著男性和女性年龄≥50岁，在阿拉斯加内陆和所有年龄组进行筛选。这些研究结果表明，哪种CRC筛查方法、间隔时间和开始筛查的年龄最适合阿拉斯加土著人，以及需要进一步研究该人群中CRC的病理学、病因学和自然史。
ObjectivesColorectal cancer (CRC) incidence and mortality are twice as high among Alaska Native people as among non-Hispanic White people in the United States; as such, colonoscopy is a recommended screening test for Alaska Native people. Adenoma detection rate (ADR) is measured in patients at average risk of CRC undergoing initial screening colonoscopy and reflects the prevalence of precancerous polyps in a screened population. We evaluated the ADR among Alaska Native people living in Interior Alaska.MethodsThis project evaluated the ADR among Alaska Native and American Indian adults aged ≥40 years (N = 460) living in Interior Alaska, using a retrospective medical record review of patients referred for screening colonoscopy from February 1, 2018, through March 31, 2022. The main outcome measure was ADR, stratified by age and sex.ResultsThe ADR was 45.0% overall: 43.0% among women and 47.1% among men. Among patients aged ≥50 years, the ADR was 67.1%: 62.7% among women and 70.7% among men. Among patients aged 40-49 years, the ADR was 34.4%: 35.3% among women and 33.3% among men.ConclusionsMeasured ADR was high among Alaska Native men and women aged ≥50 years in Interior Alaska and in all age groups that were screened. These findings have implications for which CRC screening methods, intervals, and age to begin screening are most appropriate for Alaska Native people, as well as the need for future research on the pathology, etiology, and natural history of CRC in this population.