Enthalpy of interaction of some amides with ammoniummethanoate in water at 25°C Interactions between ionic groups andpeptide and hydrophobic groups
Enthalpy of interaction of some amides with ammoniummethanoate in water at 25°C Interactions between ionic groups andpeptide and hydrophobic groups
复制标题
25°C 水中某些酰胺与甲酸铵的相互作用焓 离子基团与肽和疏水基团之间的相互作用
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
H. Linsdell
中科院分区：
文献类型：
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作者：
Javier Fernández;.. N. García;T. H. Lilley;H. Linsdell
The enthalpies of dilution at 25°C of aqueous solutions
containing ammonium methanoate and a series of amides: formamide,
acetamide, N-methylformamide, N-methylacetamide,
N-ethylformamide, N-methylpropionamide,
N,N-dimethylformamide,
N,N-dimethylacetamide and
N,N-diethylformamide have been measured. The
dilution experiments were performed on solutions equimolal in the salt
and the amides. The enthalpies of dilution of solutions containing
only ammonium methanoate were also obtained. The results on the
dilutions of the binary solute solutions were analysed using an excess
function approach and enthalpic heterotactic interaction coefficients
were obtained representing interactions between the ammonium
methanoate and the amides.
Consideration of these interaction coefficients using a group
additivity approach shows that ammonium methanoate interacts more
favourably, in a thermochemical sense, in water with tertiary amide
(secondary peptide) groups than with secondary amide (primary peptide)
groups, and that the interactions of ammonium methanoate with
methylene groups in water are thermochemically repulsive. These
results are qualitatively similar to those found for a range of salts
interacting with groups present on peptides. Examination of the
information currently available on salt–amide interactions in
aqueous solutions, gives further support to the idea that these are
fairly quantitative correlations between the propensity solutes in
water have to interact with each other and their hydration energetics.
