Sensory experience modulates the reorganisation of temporal auditory regions for executive processing
Sensory experience modulates the reorganisation of temporal auditory regions for executive processing
复制标题
DOI：
10.1101/2021.02.08.430248
复制
发表时间：
2021-02
期刊：
影响因子：
--
通讯作者：
Barbara Manini;V. Vinogradova;B. Woll;Donnie Cameron;M. Eimer;V. Cardin
中科院分区：
文献类型：
--
作者：
Barbara Manini;V. Vinogradova;B. Woll;Donnie Cameron;M. Eimer;V. Cardin
跨模态可塑性是指感觉皮层在缺乏主要感觉输入的情况下的重组。了解这种现象可以深入了解大脑功能及其变化和增强的潜力。使用功能磁共振成像，我们调查了早期耳聋如何影响跨模态可塑性和组织的执行功能在成年人的大脑。一系列视觉执行功能任务（工作记忆、任务转换、计划、抑制）的结果表明，聋人在任务转换过程中专门招募“听觉”区域。上级颞区的神经活动，最显着的是在右半球，是很好的预测行为表现在聋人组的任务切换，突出了所观察到的皮层重组的功能相关性。我们的研究结果表明，执行处理在典型的感觉区域，这表明大脑区域的发展和最终作用的感知环境经验的影响。
Crossmodal plasticity refers to the reorganisation of sensory cortices in the absence of their main sensory input. Understanding this phenomenon provides insights into brain function and its potential for change and enhancement. Using fMRI, we investigated how early deafness influences crossmodal plasticity and the organisation of executive functions in the adult human brain. Results from a range of visual executive function tasks (working memory, task switching, planning, inhibition) show that deaf individuals specifically recruit “auditory” regions during task switching. Neural activity in superior temporal regions, most significantly in the right hemisphere, are good predictors of behavioural performance during task switching in the deaf group, highlighting the functional relevance of the observed cortical reorganisation. Our results show executive processing in typically sensory regions, suggesting that the development and ultimate role of brain regions are influenced by perceptual environmental experience.