Accuracy of Smoking Status Reporting: Proxy Information in a Rapidly Fatal Cancer Setting.
Accuracy of Smoking Status Reporting: Proxy Information in a Rapidly Fatal Cancer Setting.
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DOI：
10.1016/j.mayocpiqo.2020.07.010
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发表时间：
2020-12
期刊：
影响因子：
--
通讯作者：
Petersen GM
中科院分区：
文献类型：
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作者：
Stevens MA;Rabe KG;Boursi B;Kolluri A;Singh DP;Bamlet WR;Petersen GM
评估患者和亲属是否可以作为其他家庭成员吸烟史的可靠代理报告者。从2000年11月6日至2018年3月15日入组的马约诊所胰腺研究生物标本资源中确定了两份样本（325例患者，707名亲属）。吸烟史数据，包括分类（曾经/从未）和定量（每天吸烟包数和吸烟年数）的吸烟措施，从患者和亲属自行完成的问卷中获得。将亲属报告与患者自我报告进行比较;将患者报告与亲属报告进行比较。总体而言，配偶和一级亲属（FDR）在报告患者曾经吸烟时准确率为94.5%;配偶报告的敏感性为98.6%，准确率为97.7%。配偶吸烟患者报告的准确性为97.8%，FDR吸烟患者报告的准确性为85.5%;准确性因FDR的关系而异。当不一致时，患者通常会过度报告亲属吸烟的每日包数，并报告吸烟的年份。在25%的一致性范围内，配偶报告的患者每日吸烟包为46.7%，吸烟年数为69.6%，而FDR分别为50%和64.6%。当不一致时，亲属通常会过度报告患者吸烟的每日包数，但没有观察到患者吸烟的过度或低报年数的一致模式。患者和亲属可以作为其家庭成员（尤其是配偶）吸烟史（曾经/从未）的可靠代表。准确报告吸烟状况将有助于医生更好地衡量身体状况和家庭吸烟暴露，以告知疾病管理。
To assess whether patients and relatives can serve as reliable proxy reporters of other family members’ cigarette-smoking history. Two samples (325 patients, 707 relatives) were identified from the Mayo Clinic Biospecimen Resource for Pancreas Research, enrolled from November, 6, 2000, to March 15, 2018. Smoking-history data, including categorical (ever/never) and quantitative (packs per day and years smoked) smoking measures, were obtained from self-completed questionnaires by patients and relatives. Relative reports were compared with patient reports on self; patient reports were compared with relative reports on self. Overall, spouses and first-degree relatives (FDRs) were accurate (94.5%) when reporting patient ever smoking; spouse reports were 98.6% sensitive and 97.7% accurate. Accuracy of patient reports was 97.8% for spouse smoking and 85.5% for FDR smoking; accuracy varied by relationship of FDR. When not concordant, patients generally over-reported daily packs smoked by relatives and under-reported years smoked. Within a 25% agreement range, spouse reports about patients’ daily packs smoked was 46.7%, and years smoked was 69.6%, whereas FDRs were 50% and 64.6%, respectively. When not concordant, relatives generally over-reported daily packs smoked by patients, but no consistent pattern was observed of over- or under-reporting years smoked by patients. Patients and relatives can be reliable proxies for smoking history (ever/never) in their family members, especially spouses. An accurate reporting of smoking status will help physicians to better gauge performance status and family smoking exposures to inform disease management.