Treatment of severe obsessive-compulsive disorder with fluvoxamine.
Treatment of severe obsessive-compulsive disorder with fluvoxamine.
复制标题
用氟伏沙明治疗严重强迫症。
DOI：
10.1176/ajp.144.8.1059
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Heninger,GR
中科院分区：
文献类型：
--
作者：
Price,LH;Goodman,WK;Charney,DS;Rasmussen,SA;Heninger,GR
10名强迫症患者在服用至少两周的安慰剂后，接受了氟伏沙明的单盲治疗，氟伏沙明是一种选择性的5-羟色胺再摄取抑制剂，为期几周。通过几个临床量表和自我评级衡量，该组显示出显著的改善；6名患者被判断为应答者。氟伏沙明似乎对治疗严重强迫症有效。
Ten obsessive-compulsive patients received single-blind treatment with fluvoxamine, a selective serotonin reuptake inhibitor, for several weeks following at least 2 weeks of placebo. The group showed significant improvement, as measured by several clinical scales and self-ratings; six patients were judged responders. Fluvoxamine appears effective in treating severe obsessive-compulsive disorder.