Oxytetracycline residues in giant freshwater prawn (Macrobrachium rosenbergii)
Oxytetracycline residues in giant freshwater prawn (Macrobrachium rosenbergii)
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DOI：
10.1021/jf010451i
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发表时间：
2001-10-01
影响因子：
6.1
通讯作者：
Dachanantawitaya, N
中科院分区：
文献类型：
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作者：
Brillantes, S;Tanasomwang, V;Dachanantawitaya, N
以土霉素（OTC）浓度为2.5和5.0 g/kg的饲料，分别饲喂罗氏沼虾（Macrobrachium rosenbergium）1周和1周后，研究了土霉素在罗氏沼虾体内的分布。雄虾和雌虾头部的OTC水平始终高于肌肉。与低剂量处理的批次相比，高剂量处理的雄性和雌性对虾的头部和肌肉组织中的OTC残留量显著较高。在给药期间，各组的头部和肌肉中的峰浓度在4-6天内达到。停止给药后，在所有批次的两种性别和剂量中，头部需要13天，肌肉需要10天，以将OTC残留量降至安全水平。在实践中，考虑到水温、药物剂量、治疗持续时间和其他环境条件的变化，建议停药期为21天。
The distribution of oxytetracycline (OTC) in male and female Macrobrachium rosenbergii was examined after the prawns had been given medicated feed containing OTC at levels of 2.5 and 5.0 g/kg of feed for 1 week and nonmedicated feed thereafter. OTC levels in the heads of both male and female prawns were consistently higher than in the muscles. Batches of both male and female prawns treated with higher dosages had significantly higher OTC residues in both head and muscle tissues than the batches treated with lower dosages. During treatment, peak concentrations in the head and muscle from each group were reached within 4-6 days. After drug treatment ceased, 13 days for the head and 10 days for the muscle were required to reduce OTC residues to safe levels in all batches of both sexes and dosages. In practice, to account for variations in water temperature, drug dosage, duration of therapy, and other environmental conditions, a withdrawal period of 21 days is recommended.