Heart Failure in Africa, Asia, the Middle East and South America: The INTER-CHF study
Heart Failure in Africa, Asia, the Middle East and South America: The INTER-CHF study
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DOI：
10.1016/j.ijcard.2015.11.183
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发表时间：
2016-02-01
影响因子：
3.5
通讯作者：
Yusuf, Salim
中科院分区：
文献类型：
--
作者：
Dokainish, Hisham;Teo, Koon;Yusuf, Salim
背景资料：关于来自非洲、亚洲、中东和南美洲的心力衰竭（HF）患者的数据很少。方法：INTER-CHF是一项前瞻性研究，2012年至2014年在16个国家的108个中心招募了HF患者。入选了连续性非卧床或住院的成人HF患者。记录社会人口统计学、临床特征、HF病因学和治疗的基线数据。结果：我们招募了5813名HF患者：平均（SE）年龄= 59（0.2）岁，39%女性，65%门诊患者，31%来自农村地区，26%射血分数正常的HF患者，其中1294名来自非洲，2661名来自亚洲，1000名来自中东，858名来自南美洲。与来自其他地区的参与者相比，来自非洲的参与者（紧随其后的是亚洲人）更年轻，识字水平更低，不太可能有健康或药物保险或使用β受体阻滞剂，但最有可能是NYHA IV级。来自南美的受试者年龄较大，保险和文化水平较高，沿着中东受试者，更有可能使用β受体阻滞剂，但NYHA IV级的比例最低。缺血性心脏病是最常见的HF病因在所有地区，除了非洲，高血压性心脏病是最常见的。结论：INTER-CHF描述了显着的区域变异性，在HF患者的社会经济和临床因素，病因和治疗，从非洲，亚洲，中东和南美洲。存在着改善健康/药物保险率和使用β受体阻滞剂的病人比例的机会，特别是在非洲和亚洲。(C)2015爱思唯尔爱尔兰有限公司版权所有。
Background: There are few data on heart failure (HF) patients from Africa, Asia, the Middle East and South America.Methods: INTER-CHF is a prospective study that enrolled HF patients in 108 centers in 16 countries from 2012 to 2014. Consecutive ambulatory or hospitalized adult patients with HF were enrolled. Baseline data were recorded on sociodemographics, clinical characteristics, HF etiology and treatments. Age-and sex-adjusted results are reported.Results: We recruited 5813 HF patients: mean(SE) age = 59(0.2) years, 39% female, 65% outpatients, 31% from rural areas, 26% with HF with preserved ejection fraction, with 1294 from Africa, 2661 from Asia, 1000 from the Middle-East, and 858 from South America. Participants from Africa-closely followed by Asians-were younger, had lower literacy levels, and were less likely to have health or medication insurance or be on beta-blockers compared with participants from other regions, but were most likely to be in NYHA class IV. Participants from South America were older, had higher insurance and literacy levels, and, along with Middle Eastern participants, were more likely to be on beta-blockers, but had the lowest proportion in NYHA IV. Ischemic heart disease was the most common HF etiology in all regions except Africa where hypertensive heart disease was most common.Conclusions: INTER-CHF describes significant regional variability in socioeconomic and clinical factors, etiologies and treatments in HF patients from Africa, Asia, the Middle East and South America. Opportunities exist for improvement in health/medication insurance rates and proportions of patients on beta blockers, particularly in Africa and Asia. (C) 2015 Elsevier Ireland Ltd. All rights reserved.