SAffold viruses in pediatric patients with diarrhea in Thailand
SAffold viruses in pediatric patients with diarrhea in Thailand
复制标题
泰国腹泻儿科患者中的 SAffold 病毒
DOI：
10.1002/jmv.24114
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发表时间：
2015
期刊：
影响因子：
12.7
通讯作者：
Maneekarn N
中科院分区：
文献类型：
--
作者：
Yodmeeklin A;Khamrin P;Chuchaona W;Saikruang W;Malasao R;Chaimongkol N;Kongsricharoern T;Ukarapol N;Maneekarn N
红花病毒（SAFV）是一种新发现的人类病毒，属于小核糖核酸病毒科（Picornaviridae）的病毒属。2012年1月至2013年12月期间从泰国清迈的腹泻儿童中收集了共计608份粪便标本，通过RT‐nested PCR和序列分析对SAFV进行了调查。其中，608例中有9例（1.5%）为SAFV阳性，并确定了4种基因型，SAFV 1，SAFV 2，SAFV 3和SAFV 4。在5例病例中发现了SAFV单一感染（CMH-S 038 -12、CMH-S 071 -12、CMH-S102 -12、CMH-N 029 -12和CMH-S 048 -13），而在4例病例中观察到了引起腹泻的其他病毒的合并感染（CMH-S 021 -12、CMH-S115 -12、CMH-N 048 -13和CMH-N103 -13）。这项研究提供了更多关于在泰国腹泻儿童患者中传播的SAFV遗传背景的信息。87：702-707，2015.© 2015 Wiley Periodicals，Inc.
Saffold virus (SAFV) is a newly discovered human virus which is classified into the genusCardiovirusof the familyPicornaviridae. A total of 608 fecal specimens collected during January 2012 to December 2013 from children with diarrhea in Chiang Mai, Thailand were investigated for SAFV by RT‐nested PCR and sequence analysis. Of these, nine out of 608 (1.5%) were positive for SAFVs and four genotypes were identified, SAFV1, SAFV2, SAFV3, and SAFV4. SAFV mono‐infection was found in five cases (CMH‐S038–12, CMH‐S071–12, CMH‐S102–12, CMH‐N029–12, and CMH‐S048–13), while co‐infection with other viruses causing diarrhea was observed in four cases (CMH‐S021–12, CMH‐S115–12, CMH‐N048–13 and CMH‐N103–13). This study provides more information about the genetic background of SAFV circulating in pediatric patients with diarrhea in Thailand.J. Med. Virol. 87:702–707, 2015.© 2015 Wiley Periodicals, Inc.