COFFEE AND ALCOHOL AS DETERMINANTS OF RISK OF PANCREAS CANCER - A CASE-CONTROL STUDY FROM TORONTO
COFFEE AND ALCOHOL AS DETERMINANTS OF RISK OF PANCREAS CANCER - A CASE-CONTROL STUDY FROM TORONTO
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DOI：
10.1002/ijc.2910470313
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发表时间：
1991-02-01
影响因子：
6.4
通讯作者：
MILLER, AB
中科院分区：
文献类型：
--
作者：
JAIN, M;HOWE, GR;MILLER, AB
结果来自 1983 年至 1986 年间在加拿大多伦多进行的一项基于人群的研究，该研究对 249 例胰腺癌病例和 505 例对照进行了研究。通过个人访谈评估了终生咖啡和酒精的消费量以及病史。 在调整吸烟、卡路里和纤维摄入量后，没有发现任何证据表明不同类型的咖啡或酒精有任何关联。 癌症发生后 5 年内，与糖尿病史相关的风险显着增加。 尽管相对风险并不显着（p 值 > 0.10），但观察到一些过敏性疾病（如花粉热、湿疹和哮喘）病史的保护作用。
Results are reported from a population-based study of 249 cases of pancreas cancer and 505 controls carried out in Toronto, Canada, between 1983 and 1986. Lifetime consumption of coffee and alcohol and medical histories were assessed by personal interviews. No evidence of any association was found with different types of coffee or alcohol after adjusting for smoking, calories and fibre intake. There was a significant increased risk associated with a history of diabetes mellitus within 5 years of cancer development. A protective effect of a history of some allergic conditions, hay fever, eczema and asthma, was observed, although the relative risks were not significant (p value > 0.10).