Fibromyalgia syndrome and serotonin.

Fibromyalgia syndrome and serotonin.
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纤维肌痛综合征和血清素。

DOI:
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发表时间:
2001
影响因子:
3.7
通讯作者:
P. Barland
P. Barland
中科院分区:
医学4区
文献类型:
--
作者:
M. N. Alnigenis;P. Barland

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虽然在肌肉骨骼系统,神经内分泌系统和中枢神经系统(CNS)的干扰已被牵连在纤维肌痛综合征(FMS)的病理生理,FMS的发病机制的主要机制仍然难以捉摸。据推测,FMS患者存在5-羟色胺代谢和传递的紊乱,沿着其他几种化学疼痛介质的紊乱。在这篇文章中,我们回顾了已发表的研究在FMS的病理生理作用的5-羟色胺。虽然间接测量FMS中CNS中5-羟色胺功能的研究揭示了5-羟色胺代谢和传递的一些异常,但5-羟色胺在综合征病理生理学中的作用仍不确定,需要更多的研究。
Although disturbances in the musculoskeletal system, in the neuroendocrine system and in the central nervous system (CNS) have been implicated in the pathophysiology of fibromyalgia syndrome (FMS), the primary mechanisms underlying the etiopathogenesis of FMS remain elusive. It has been postulated that disturbances in serotonin metabolism and transmission, along with disturbances in several other chemical pain mediators, are present in patients with FMS. In this article we review published studies on the pathophysiological role of serotonin in FMS. Although studies that indirectly measured the function of serotonin in the CNS in FMS revealed some abnormalities in the metabolism and transmission of serotonin, the role of serotonin in the pathophysiology of syndrome remains inconclusive and warrants more studies.
饮食和其他代谢现象对大脑色氨酸吸收和血清素合成的影响。
DOI: 10.1007/978-1-4684-5952-4_34
发表时间: 1991
影响因子: --
作者:
Fernstrom,JD
通讯作者: Fernstrom,JD
纤维肌痛异常疼痛感知病理生理学的最新概念。
DOI: 10.1097/00000441-199806000-00009
发表时间: 1998
期刊: The American journal of the medical sciences
影响因子: --
作者:
Weigent,DA;Bradley,LA;Blalock,JE;Alarcón,GS
通讯作者: Alarcón,GS