A high prevalence of HIV-1 infection among pregnant women living in a rural district of north Uganda severely affected by civil strife
A high prevalence of HIV-1 infection among pregnant women living in a rural district of north Uganda severely affected by civil strife
复制标题
DOI：
10.1016/j.trstmh.2005.09.002
复制
发表时间：
2006-06-01
影响因子：
2.2
通讯作者：
Declich, S
中科院分区：
文献类型：
--
作者：
Fabiani, M;Nattabi, B;Declich, S
这项研究的目的是估计最近的趋势，艾滋病毒-1流行和感染的因素，在乌干达北部的古卢区，一个农村地区的内乱严重影响的孕妇。2000-2003年，共有4 459名拉科医院产前门诊就诊者接受了匿名HIV-1感染检测。总体和特定年龄的患病率没有显示出任何随时间变化的显著趋势。年龄标准化流行率略有下降，从2000年的12.1%降至2003年的11.3%。年龄增加[20-24岁：调整后比值比（AOR）1.63; 95% CI 1.18-2.25; ≥ 25岁：AOR 2.56; 95% CI 1.91-3.44]，居住在城市地区（AOR 1.76; 95% CI 1.41-2.18），未婚（AOR 1.60; 95% CI 1.27-2.01），伴侣年龄增加（25-34岁：AOR 1.87; 95% CI 1.29-2.73; ≥ 35岁：AOR 2.68; 95% CI 1.72-4.16），伴侣的现代职业（AOR 1.98; 95% CI 1.53-2.58）和在当前地址居住时间短（AOR 1.36; 95% CI 1.05-1.76）与感染相关。该农村地区的艾滋病毒-1流行率很高，与城市产前诊所的情况相似，这可能反映了过去18年内乱的影响。(C)2005年皇家热带医学和卫生学会。由爱思唯尔有限公司出版。保留所有权利。
This study aims at estimating the recent trends in HIV-1 prevalence and the factors associated with infection among pregnant women in the Gulu District of north Uganda, a rural area severely affected by civil strife. In 2000-2003, a total of 4459 antenatal clinic attendees of Lacor Hospital were anonymously tested for HIV-1 infection. The overall and age-specific prevalence did not show any significant trend over time. The age-standardized prevalence slightly declined, from 12.1% in 2000 to 11.3% in 2003. Increased age [20-24 years: adjusted odds ratio (AOR) 1.63; 95% CI 1.18-2.25; >= 25 years: AOR 2.56; 95% Cl 1.91-3.44], residence in urban areas (AOR 1.76; 95% Cl 1.41-2.18), being unmarried (AOR 1.60; 95% Cl 1.27-2.01), increased age of partner (25-34 years: AOR 1.87; 95% Cl 1.29-2.73; >= 35 years: AOR 2.68; 95% Cl 1.72-4.16), modern occupation of partner (AOR 1.98; 95% CI 1.53-2.58), and short time of residence at the current address (AOR 1.36; 95% Cl 1.05-1.76) were associated with infection. The HIV-1 prevalence in this rural district is high and similar to that observed in urban antenatal clinics, probably reflecting the effect of the last 18 years of civil strife. (C) 2005 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.