The morphine abstinence syndrome, its nature and treatment

The morphine abstinence syndrome, its nature and treatment
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DOI:
10.7326/0003-4819-15-5-829
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发表时间:
1941-11-01
影响因子:
39.2
通讯作者:
Himmelsbach, CK
Himmelsbach, CK
中科院分区:
医学1区
文献类型:
--
作者:
Himmelsbach, CK

文献摘要

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吗啡戒断综合征是一种明确的临床表现。这种综合征的一些更常见的体征和症状是:打哈欠、流泪、流涕、出汗、起鸡皮疙瘩、震颤、瞳孔放大、紧张、坐立不安、腿疼、厌食、恶心、腹部绞痛、呕吐、腹泻、失眠、发热、呼吸过度、血压升高和体重减轻。适当的戒断综合征管理方案包括初步稳定期,迅速减少吗啡,无害的补充措施,如输液,镇静剂和流动浴,以及经常和仔细观察的良好护理。戒断治疗最重要的特点是明智地使用阿片类药物。
The morphine abstinence syndrome is a definite clinical entity. Some of the more common signs and symptoms of this syndrome are: yawning, lacrimation, rhinorrhea, perspiration, gooseflesh, tremor, dilated pupils, nervousness, restlessness, aching of legs, anorexia, nausea, abdominal cramps, emesis, diarrhea, insomnia, fever, hyper-pnea, elevation of blood pressure, and loss of weight. An adequate program for management of the abstinence syndrome consists of a preliminary period of stabilization, rapid reduction of morphine, harmless supplementary measures such as infusions, sedatives, and flow baths, and good nursing with frequent and careful observation. The most important feature of withdrawal treatment is the judicious use of opiates.