Gangliotetraosyl-ceramide, the rat T lymphocyte-macrophage-associated antigen: chemical detection and cellular distribution.

Gangliotetraosyl-ceramide, the rat T lymphocyte-macrophage-associated antigen: chemical detection and cellular distribution.
复制标题

神经节四糖基神经酰胺,大鼠 T 淋巴细胞巨噬细胞相关抗原:化学检测和细胞分布。

DOI:
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发表时间:
1980
影响因子:
4.4
通讯作者:
H. Thiele
H. Thiele
中科院分区:
医学2区
文献类型:
--
作者:
T. Momoi;H. Wiegandt;R. Arndt;H. Thiele

文献摘要

被引文献

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神经节四糖基神经酰胺的存在,即,Gal β 1导致3GalNAc β 1导致4Gal β 1导致4Glc β 1导致Cer,T淋巴细胞-巨噬细胞相关抗原,在大鼠的淋巴结细胞、胸腺淋巴细胞和腹膜渗出物细胞上建立。为此,通过微量分离和检测方法提取和分离细胞的鞘糖脂。与免疫球蛋白阴性大鼠淋巴结细胞相反,免疫球蛋白携带淋巴结细胞未检测到神经节四糖基神经酰胺。
The presence of gangliotetraosyl-ceramide, i.e., Gal beta 1 leads to 3GalNAc beta 1 leads to 4Gal beta 1 leads to 4Glc beta 1 leads to Cer, the T lymphocyte-macrophage-associated antigen, on lymph node cells, thymic lymphocytes, and peritoneal exudate cells of the rat was established. For this, the glycosphingo-lipids of the cells were extracted and isolated by a microseparation and detection method. In contrast to immunoglobulin-negative rat lymph node cells, immunoglobulin-bearing lymph node cells showed no detectable gangliotetraosyl-ceramide.