Polymorphisms of growth‐ and immune‐related genes in cultured red sea bream Pagrus major identified by gene‐related DNA markers
Polymorphisms of growth‐ and immune‐related genes in cultured red sea bream Pagrus major identified by gene‐related DNA markers
复制标题
通过基因相关DNA标记鉴定养殖真鲷生长和免疫相关基因的多态性
DOI：
10.1111/jai.14184
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发表时间：
2021
影响因子：
0.9
通讯作者：
Takagi Motohiro
中科院分区：
文献类型：
--
作者：
Sawayama Eitaro;Kobayashi Wataru;Nakao Hironori;Yamada Yuuki;Takagi Motohiro
罗非鱼是日本重要的海水养殖鱼类，养殖历史近半个世纪。通过选择生长最快的1%的个体作为后代的亲本，培育出一种快速生长的菌株(Murata等人，1996)。这个生长选择种群已经分布到日本各地的孵化场，目前在日本养殖的所有红鳍金枪鱼都来自这个单一基因库(Sawayama&Takagi，2016)，它已经产生了十多代。使用中性微卫星DNA标记分析了养殖红鱼的种群遗传参数，发现与野生种群相比，多样性大大降低(Sawayama&Takagi，2016)。然而，中性DNA标记没有显示出基因与特定性状的关联，关于选择如何影响基因的数据也有限，例如那些影响生长和免疫状态的基因，以及具有经济价值的基因。人工选择已经影响了农作物(Tian等人，2009年)和家养动物(Akey等人，2010年；Andersson和Georges，2004；Tian等人，2009)的特征相关基因。水产养殖已经建立了一系列鱼类物种，最近的研究试图检测与大西洋驯化有关的基因
Red sea bream, Pagrus major, is an important farmed marine fish in Japan, cultured for nearly half a century. A rapid-growth strain was developed by selecting the most rapidly growing 1% of individuals for broodstock of successive generations (Murata et al., 1996). This growth-selected population has been distributed to hatcheries throughout Japan, and all red sea bream currently cultured in Japan originated from that single gene pool (Sawayama & Takagi, 2016), which has produced more than ten generations. Population genetic parameters of the farmed red sea bream have been analyzed using neutral microsatellite DNA markers and found to be considerably less diverse compared with the wild population (Sawayama & Takagi, 2016). However, neutral DNA markers have not shown association of genes with specific traits, and data are limited with respect to how selection affects genes such as those influencing growth and immune status, traits of economic value in red sea bream.Artificial selection has affected trait-related genes in agricultural crops (Tian et al., 2009) and domesticated animals (Akey et al., 2010; Andersson & Georges, 2004; Tian et al., 2009). Aquaculture has been established for a range of fish species, and recent research has attempted to detect genes relevant to domestication of Atlantic