THE NATURAL-HISTORY OF PAINFUL DIABETIC NEUROPATHY - A 4-YEAR STUDY
THE NATURAL-HISTORY OF PAINFUL DIABETIC NEUROPATHY - A 4-YEAR STUDY
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DOI：
10.1136/pgmj.59.695.556
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发表时间：
1983-01-01
影响因子：
5.1
通讯作者：
WARD, JD
中科院分区：
文献类型：
--
作者：
BOULTON, AJM;SCARPELLO, JHB;WARD, JD
选择患有疼痛性糖尿病周围神经病变的患者（39例）进行随访研究，以确定这种疾病的自然史。症状，运动传导速度（MCV）和踝关节压力指数记录在初始评估和平均研究期后4.7年。患者（36例）完成了研究，症状无显著变化，但正中神经MCV显著下降。糖尿病神经病变的症状持续数年，MCV的变化可能反映了神经功能的持续恶化。
Patients (39) with painful diabetic peripheral neuropathy were selected for a follow-up study to determine the natural history of this condition. Symptoms, motor conduction velocities (MCV) and ankle pressure indices were recorded at the initial assessment and after a mean study period of 4.7 yr. Patients (36) completed the study and showed no significant changes in symptoms, but there was a significant fall in median nerve MCV. Symptoms of established diabetic neuropathy persist for several years, and the changes in MCV may reflect continuing deterioration in nerve function.