Musashi1 antigen expression in human fetal germinal matrix development

Musashi1 antigen expression in human fetal germinal matrix development
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DOI:
10.1016/j.expneurol.2006.04.023
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发表时间:
2006-10-01
影响因子:
5.3
通讯作者:
Stopa, Edward G.
Stopa, Edward G.
中科院分区:
医学2区
文献类型:
--
作者:
Chan, Charles;Moore, Brian E.;Stopa, Edward G.

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Musashil是在神经祖细胞中发现的高度保守的蛋白。我们研究了Musashil与其他代表性的神经祖细胞抗原决定簇(Ki-67和巢蛋白)在8个不同阶段的发展中的人胎儿germinal的表达动态;矩阵。我们的研究结果表明,Musashil是一个有用的标志物,为未成熟细胞在脑室周围的干细胞,祖细胞和分化细胞居住。(c)2006年爱思唯尔公司All rights reserved.
Musashil is a highly conserved protein found in neural progenitor cells. We examined the expression dynamics of Musashil in conjunction with other representative neural progenitor antigenic determinants (Ki-67 and nestin) during 8 different stages of the developing human fetal germinal; matrix. Our results indicate that Musashil is a useful marker for immature cells in periventricular areas inhabited by stem cells, progenitor cells, and differentiating cells. (c) 2006 Elsevier Inc. All rights reserved.