'Like sugar and honey': the embedded ethics of a larval control project in The Gambia.
'Like sugar and honey': the embedded ethics of a larval control project in The Gambia.
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DOI：
10.1016/j.socscimed.2010.02.012
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发表时间：
2010-06
影响因子：
5.4
通讯作者：
Pinder, Margaret
中科院分区：
文献类型：
--
作者：
Kelly, Ann H.;Ameh, David;Majambere, Silas;Lindsay, Steve;Pinder, Margaret
本文介绍了冈比亚的一个疟疾研究项目，旨在激发人们对跨国研究的社会价值的思考。幼虫控制项目（LCP）研究了微生物杀虫剂在减少病媒密度以及最终减少冈比亚儿童临床疟疾方面的功效。 LCP 的协议描绘了一项临床监测计划，该计划涉及由项目护士支持的乡村卫生工作者 (VHW)。结合 2005 年至 2009 年在法拉芬尼医学研究委员会 (MRC) 实验室进行的人种学实地调查、对项目护士的开放式访谈以及 2007 年 10 月与参与者母亲进行的八次焦点小组讨论的见解，我们在几年的研究活动背景下考虑了 LCP 调查方法的社会影响。我们发现，虽然参与者将 LCP 与其提供的临床护理联系起来，但他们也认为护士和 VHW 之间的合作增加了额外的好处。围绕试验的运营职能组织的小规模合作提供了建设当地能力的平台。虽然伦理指南强调了南方国家实验工作中必须考虑的因素（例如，详细说明知情同意程序、制定社区参与策略或在试验结束后为参与者提供治疗机会），但这些发现表明，将注意力从补充伦理协议转移到日常研究工作——将伦理融入科学活动中——可能会为加强科学与科学之间的关系提供更坚实的基础。 严谨性和社会价值。
This paper describes a malaria research project in The Gambia to provoke thinking on the social value of transnational research. The Larval Control Project (LCP) investigated the efficacy of a microbial insecticide to reduce vector density and, ultimately, clinical malaria in Gambian children. The LCP’s protocol delineated a clinical surveillance scheme that involved Village Health Workers (VHWs) supported by project nurses. Combining insights from ethnographic fieldwork conducted at the Medical Research Council (MRC) Laboratories in Farafenni from 2005 to 2009, open-ended interviews with project nurses, and eight focus group discussions held with participant mothers in October 2007, we consider the social impact of the LCP’s investigative method against the backdrop of several years of research activity. We found that while participants associated the LCP with the clinical care it provided, they also regarded the collaboration between the nurses and VHWs added additional benefits. Organised around the operational functions of the trial, small-scale collaborations provided the platform from which to build local capacity. While ethical guidelines emphasise the considerations that must be added to experimental endeavour in southern countries (e.g. elaborating processes of informed consent, developing strategies of community engagement or providing therapeutic access to participants after the trial concludes), these findings suggest that shifting attention from supplementing ethical protocols to the everyday work of research – embedding ethics through scientific activity – may provide a sounder basis to reinforce the relationship between scientific rigour and social value.
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