Indications and results of retransplantation after a series of 406 consecutive liver transplantations.
Indications and results of retransplantation after a series of 406 consecutive liver transplantations.
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连续 406 例肝移植后再次移植的指征和结果。
DOI：
10.1016/s0041-1345(01)02753-1
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发表时间：
2002
影响因子：
0.9
通讯作者：
J. Ardáiz
中科院分区：
文献类型：
--
作者：
M. Jimenez;V. Turrión;L. G. Alvira;J. Lucena;J. Ardáiz
结果慢性排斥反应18例(44%)，动脉血栓形成6例(14.6%)，原发疾病复发6例(14.6%)，早期移植失败6例(14.6%)，肝静脉血栓形成2例(4.8%)，急性排斥反应1例(2.4%)，其他并发症2例(4.8%)。21例患者进行了早期(PLT后6个月)的OLR，20例患者完成了晚期的OLR(PLT后6个月或以上)。死亡29例(70.7%)，术中死亡2例(4.8%)，术后(0~11天)死亡5例(12.1%)。围手术期住院死亡22例(56%)，总生存率29.26%(12例)，术后1年和5年精算生存率分别为46%和28%。存活率最高的是肝动脉血栓形成和导管生成排斥反应。另一方面，移植物失败和原发疾病的复发与低存活率有关。
RESULTSOLR was indicated due to the following reasons: chronic rejection in 18 patients (44%), arterial thrombosis in six patients (14.6%), recurrence of primary disease in six patients (14.6%), early graft failure in six patients (14.6%), hepatic vein thrombosis in two patients (4.8%), acute rejection in one patient (2.4%), and other complications in two patients (4.8%). An early OLR (during the first 6 months after PLT) was carried out in 21 patients and a late OLR (6 or more months after PLT) was completed in 20 cases. A total of 29 fatal cases were registered (70.7%), two (4.8%) intraoperative deaths, and five (12.1%) postoperative (0 to 11 days after surgery) deaths were registered. A total of 22 cases (56%) of perioperative hospital mortality were registered.Overall survival rate of this series was 29.26%(12 patients) and 1-and 5-year post-OLR actuarial survival rates of these patients were, respectively, 46% and 28%. The highest survival rates were related to hepatic artery thrombosis and ductopaenic rejection. On the other hand, graft failure and recurrence of primary disease were associated with low survival rates.