SEXUAL RECEPTIVITY IN FEMALE RATS AFTER LESION OR STIMULATION IN DIFFERENT AMYGDALOID NUCLEI
SEXUAL RECEPTIVITY IN FEMALE RATS AFTER LESION OR STIMULATION IN DIFFERENT AMYGDALOID NUCLEI
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DOI：
10.1016/0031-9384(80)90050-5
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发表时间：
1980-01-01
影响因子：
2.9
通讯作者：
CARRER, HF
中科院分区：
文献类型：
--
作者：
MASCO, DH;CARRER, HF
杏仁皮质内侧核前部损毁可降低去卵巢大鼠服用苯甲酸雌二醇和黄体酮后前凸反应的频率。同一区域的电化学刺激(铁沉积)则有相反的效果。当损毁杏仁外侧核的后部时，可观察到感受性的极显着增加；另一方面，在该区域的刺激降低了接受性动物的前凸商。皮损后观察到的效果不能归因于不同的雌激素剂量，也不能归因于组织破坏的非特异性影响。电化学刺激后观察到的变化不依赖于这一过程产生的损伤或采用的重复测试范式。电刺激后杏仁核皮质图和EEG未见明显改变。显然，杏仁核结构在雌性大鼠性行为控制中起着调制和整合的作用：皮质内侧核前部细胞的激活增加了前凸反应的概率，而外侧核后部神经元的兴奋则相反。
Lesions in the anterior part of the corticomedial amygdaloid nucleus decreased the frequency of lordotic responses in ovariectomized rats treated with estradiol benzoate and progesterone. Electrochemical stimulation (iron deposition) of the same area had the opposite effect. When lesions were made in the posterior part of the lateral amygdaloid nucleus a highly significant increase in receptivity was observed; on the other hand stimulation in this region depressed the lordosis quotient in receptive animals. The effects observed after lesioning cannot be attributed to the different estrogen doses used, nor to nonspecific effects of tissue destruction. The changes observed after electrochemical stimulation do not depend on the lesion produced by this procedure or the repeated-tests paradigm employed. Electrocorticograms and EEG of the amygdala showed no apparent alterations after electrochemical stimulations. Apparently amygdaloid structures play a modulatory and integrative role on the control of sexual behavior in the female rat: activation of cells in the anterior part of the corticomedial nucleus increases the probability of lordotic response while excitation of the neurons in the posterior part of the lateral nucleus has the opposite effect.