The reaction of ferrous horseradish peroxidase with hydrogen peroxide.

The reaction of ferrous horseradish peroxidase with hydrogen peroxide.
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辣根亚铁过氧化物酶与过氧化氢的反应。

DOI:
10.1016/s0021-9258(18)63167-9
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发表时间:
1970
期刊:
The Journal of biological chemistry
影响因子:
--
通讯作者:
Q. H. Gibson
Q. H. Gibson
中科院分区:
--
文献类型:
--
作者:
R. Noble;Q. H. Gibson

文献摘要

被引文献

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过氧化氢与辣根亚铁过氧化物酶发生反应,并通过两个反应将其转化为过氧化物酶。一是亚铁过氧化物酶与h2o2反应生成化合物II;二是化合物II与h2o2反应生成过氧化物酶。两个反应都遵循二级动力学,对于每个反应物都是一级动力学。它们的过程中没有可检测到的中间体,因此,似乎是单步2电子氧化。
Hydrogen peroxide reacts with ferrous horseradish peroxidase and converts it to oxyperoxidase in a sequence of two reactions. The first is the reaction of ferrous peroxidase with H2O2to form Compound II; the second is the reaction of Compound II with H2O2to form oxyperoxidase.Both reactions follow second order kinetics, being first order with respect to each of the reactants. They proceed without detectable intermediates, and, therefore, appear to be single step 2-electron oxidations.