Miniaturized High-Resolution Time-of-Flight Mass Spectrometer MULTUM-S II with an Infinite Flight Path
Miniaturized High-Resolution Time-of-Flight Mass Spectrometer MULTUM-S II with an Infinite Flight Path
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DOI：
10.1021/ac1010348
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发表时间：
2010-10-15
影响因子：
7.4
通讯作者：
Toyoda, Michisato
中科院分区：
文献类型：
--
作者：
Shimma, Shuichi;Nagao, Hirofumi;Toyoda, Michisato
设计和制造了一种新型的小型多圈飞行时间分析仪“穆尔图姆-S II”。该仪器由电子电离源、多圈TOF离子光学系统、探测器、真空系统和电子线路组成。多圈飞行时间分析器由四个静电环形扇区和两个额外的用于离子注入/喷射的电动环形扇区组成。该系统的尺寸和重量小于50厘米×57厘米×30厘米和35公斤(包括真空泵和电子电路)。多圈飞行时间分析器由于其无限的飞行轨迹，利用完美的空间和时间聚焦的封闭飞行轨道，因此能够获得高质量分辨率。为了评价MULTUM-S II的分辨率，对吡啶((C5H5N)-C-12)和苯的同位素组分((CC5H6)-C-13-C-12)进行了分离，质量分辨率约为20000。通过分离温室气体双峰CO_2和N_2O(增量m=0.0113 Da)，证明了MULTOM-S II的另一个性能特征。虽然质量差只有0.01Da，但该仪器可以很容易地在计算质量分辨率为31600的情况下将两个峰分开。穆尔图姆-S II在微型/便携式外壳中提供高质量分辨率质谱仪。
A new miniature multiturn time-of-flight (TOF) analyzer "MULTUM-S II" has been designed and constructed. This instrument consists of an electron ionization source, the multiturn TOF ion optics, a detector, vacuum system, and electronic circuits. The multiturn TOF analyzer consists of four electrostatic toroidal sectors and two additional electric toroidal sectors for the purpose of ion injection/ejection. The size and weight of the system is less than 50 cm x 57 cm x 30 cm and 35 kg (including vacuum pumps and electronic circuits). The multiturn TOF analyzer is capable of high mass resolution because of its infinite flight path utilizing perfect space and time focused closed flight orbit. To evaluate the resolution in MULTUM-S II, separation of pyridine ((C5H5N)-C-12) and the isotopic component of benzene ((CC5H6)-C-13-C-12) was performed at a mass resolution of about 20 000. Another performance characteristic of the MULTUM-S II was demonstrated by the separation of the greenhouse gas doublet CO2 and N2O (Delta m = 0.0113 Da). While the mass difference is a mere 0.01 Da, the instrument could easily separate the two peaks at a calculated mass resolution of 31 600. The MULTUM-S II offers high mass resolution mass spectrometry in a miniaturized/portable enclosure.