A stable topography of selectivity for unfamiliar shape classes in monkey inferior temporal cortex
A stable topography of selectivity for unfamiliar shape classes in monkey inferior temporal cortex
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DOI：
10.1093/cercor/bhm196
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发表时间：
2008-07-01
期刊：
影响因子：
3.7
通讯作者：
DiCarlo, James J.
中科院分区：
文献类型：
--
作者：
Op de Beeck, Hans P.;Deutsch, Jennifer A.;DiCarlo, James J.
猴的下颞叶皮层（IT）在视觉物体识别和学习中起着核心作用。先前的研究已经观察到IT皮层中的补丁对高度熟悉的对象类别具有很强的选择性（例如，面），但是由于区分不同对象类的许多属性，这种功能组织背后的原理在很大程度上是未知的。为了将形状与意义和记忆区分开来，我们用功能性磁共振成像对猴子进行了扫描，同时让它们观察最初新奇的物体。我们的数据揭示了这些新的对象类跨IT皮层的选择性地形。我们发现，这种选择性地形是高度可重复性和非常稳定的3个月的时间间隔，在此期间，猴子进行了广泛的训练，以区分样本中的一个对象类。此外，这种选择性地形在很大程度上不受行为任务和对象视网膜位置的变化，这两者都保持形状。相反，它受到物体形状变化的强烈影响。地形是部分相关的，但不能解释的，前面描述的模式的脸的选择性。总之，这些结果表明，IT皮层包含一个大规模的形状地图，在很大程度上独立于意义，熟悉度和行为任务。
The inferior temporal (IT) cortex in monkeys plays a central role in visual object recognition and learning. Previous studies have observed patches in IT cortex with strong selectivity for highly familiar object classes (e.g., faces), but the principles behind this functional organization are largely unknown due to the many properties that distinguish different object classes. To unconfound shape from meaning and memory, we scanned monkeys with functional magnetic resonance imaging while they viewed classes of initially novel objects. Our data revealed a topography of selectivity for these novel object classes across IT cortex. We found that this selectivity topography was highly reproducible and remarkably stable across a 3-month interval during which monkeys were extensively trained to discriminate among exemplars within one of the object classes. Furthermore, this selectivity topography was largely unaffected by changes in behavioral task and object retinal position, both of which preserve shape. In contrast, it was strongly influenced by changes in object shape. The topography was partially related to, but not explained by, the previously described pattern of face selectivity. Together, these results suggest that IT cortex contains a large-scale map of shape that is largely independent of meaning, familiarity, and behavioral task.