Microbial stress response in minimal processing
Microbial stress response in minimal processing
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DOI：
10.1016/s0168-1605(99)00078-1
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发表时间：
1999-09-15
影响因子：
5.4
通讯作者：
Wouters, JA
中科院分区：
文献类型：
--
作者：
Abee, T;Wouters, JA
“细菌已经进化出适应性网络，以应对不断变化的环境的挑战，并在压力条件下生存。因此，需要评估灭活和保存方法的效率，特别是关于食品病原体适应各种压力条件的巨大潜力。所有的适应性反应，无论是改变营养还是在最小加工过程中遇到的各种压力，都涉及一系列控制代谢变化的基因开关。一种常见的调节机制涉及σ（sigma）因子的修饰，其主要作用是结合核心RNA聚合酶，赋予启动子特异性，指导参与热休克反应、趋化反应、孢子形成和一般应激反应的特异性调节子的表达。革兰氏阳性细菌中的后一种调节子（sigma（B）调节子）和革兰氏阴性细菌中的后一种调节子（RpoS调节子）的实例将更详细地讨论。细胞适应机制饥饿，冷休克，热休克，（弱）酸，高渗透压和高静水压力将被描述和它们的意义在食品保藏和安全性进行了讨论。“（C）1999 Elsevier Science B.V.保留所有权利。
"Bacteria have evolved adaptive networks to face the challenges of changing environments and to survive under conditions of stress. Therefore, the efficiencies of inactivation and preservation methods need to be assessed, especially with regard to the enormous potential of food pathogens to adapt to a wide variety of stress conditions. All adaptive responses, whether to changing nutrients or to various stresses encountered in minimal processing, involve a series of genetic switches that control the metabolic changes taking place. A common regulatory mechanism involves the modification of sigma (sigma) factors whose primary role is to bind to core RNA polymerase conferring promoter specificity directing expression of specialty regulons involved in heat-shock response, the chemotactic response, sporulation, and general stress response. Examples of the latter regulon in Gram-positive bacteria (the sigma(B) regulon) and in Gram-negative bacteria (the RpoS regulon) will be discussed in more detail. Cellular adaptive mechanisms to starvation, cold shock, heat shock, (weak) acids, high osmolarity and high hydrostatic pressure will be described and their significance in food preservation and safety will be discussed." (C) 1999 Elsevier Science B.V. All rights reserved.