In vivo 3D imaging of human motor units in upper and lower limb muscles
In vivo 3D imaging of human motor units in upper and lower limb muscles
复制标题
人体上肢和下肢肌肉运动单位的体内 3D 成像
DOI:
10.1016/j.clinph.2022.05.018
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发表时间:
2022
影响因子:
4.7
通讯作者:
Heskamp L
中科院分区:
文献类型:
--
作者:
Heskamp L
ObjectiveTo assessin-vivocross-sectional and 3D morphology of human motor units in hand, forearm and lower leg muscles using magnetic resonance imaging (MRI).MethodsDiffusion weighted MRI was used with in-scanner electrical stimulation in healthy controls to image motor units at a single slice in lower leg, forearm and hand muscles (n = 6) and multiple slices in the lower leg for 3D assessment (n = 7).ResultsMotor unit cross-sectional area (CSA) and maximum Feret diameter (FDmax) did not differ between the lower leg (CSA: 22.4 ± 8.4 mm2; FDmax: 8.7 ± 2.4 mm), forearm (CSA: 23.6 ± 14.1 mm2; FDmax: 9.0 ± 3.3 mm) and hand (CSA: 26.8 ± 12.8 mm2and FDmax: 9.6 ± 2.7 mm) (ANOVA;p= 0.487 andp= 0.587, respectively). Lower leg motor units were 8.0 ± 3.8 cm long with largest CSA in the motor unit’s middle section. 3D motor unit imaging revealed a complex structure with several units splitting and re-forming along their length.ConclusionsMotor unit MRI (MUMRI) can be applied to upper limb muscles, and can reveal the 3D structure of human motor unitsin-vivo.SignificanceMUMRI provides the firstin-vivo2D images of upper limb motor units and 3D images of lower leg motor units. 3D imaging suggest a more complex human motor unit structure than previously thought.
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影响因子:
3.2
作者:
Javier Navallas;A. Malanda;Luis Gila;Javier Rodríguez;I. Rodríguez
通讯作者:
I. Rodríguez
DOI:
--
发表时间:
1955
期刊:
Acta Anatomica
影响因子:
--
作者:
B. Feinstein;B. Lindegård;E. Nyman;G. Wohlfart
通讯作者:
G. Wohlfart
影响因子:
5.3
作者:
Harris, AJ;Duxson, MJ;Gandevia, SC
通讯作者:
Gandevia, SC
影响因子:
2.9
作者:
Dean JC;Clair-Auger JM;Lagerquist O;Collins DF
通讯作者:
Collins DF
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
T. Šoić;M. Nikolic;I. Marić;R. Cerović;S. Bajek
通讯作者:
S. Bajek