Pannexin 1 forms an anion-selective channel
Pannexin 1 forms an anion-selective channel
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DOI:
10.1007/s00424-012-1077-z
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发表时间:
2012-04-01
影响因子:
4.5
通讯作者:
Surprenant, Annmarie
中科院分区:
文献类型:
--
作者:
Ma, Weihong;Compan, Vincent;Surprenant, Annmarie
Pannexin 1 (Panx1) is expressed in various mammalian tissues including the brain and immune cells. Here, we present evidence that Panx1 when expressed in mammalian cells, forms anion-selective channels, with a rank order of permeabilities: NO (3) (-) > I- > Br- > Cl- > F- a parts per thousand