Review of titania nanotubes: Fabrication and cellular response
Review of titania nanotubes: Fabrication and cellular response
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DOI：
10.1016/j.ceramint.2012.03.002
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发表时间：
2012-08
影响因子：
5.2
通讯作者：
A. Tan;B. Pingguan-Murphy;R. Ahmad;S. Akbar
中科院分区：
文献类型：
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作者：
A. Tan;B. Pingguan-Murphy;R. Ahmad;S. Akbar
二氧化钛（TiO2）纳米管由于其独特的性能（例如高比表面积和表现出积极的细胞反应的能力）作为植入材料而受到重视。在本文中，我们简要回顾了合成纳米管TiO2表面形貌的制备方法的现状，并讨论了其对不同细胞在细胞粘附、增殖和分化方面的细胞反应的影响。还提出了使用 TiO2 纳米管进行的体外和体内研究，确定了纳米管在生物医学应用中的潜力。最后，展望了纳米管之外的 TiO2 纳米结构研究的未来发展
Titania (TiO2) nanotube is gaining prominence as an implantation material due to its unique properties such as high specific surface area and the ability to exhibit positive cellular response. In this paper, we briefly review the current state of fabrication methods to synthesize nanotubular TiO2surface topography, and discuss its effect on cellular response of different cells in terms of cell adhesion, proliferation and differentiation. In vitro and in vivo studies by using TiO2nanotubes are also presented establishing the potential of nanotubes in biomedical applications. Finally, an outlook of future growth of research in TiO2nanostructures beyond the nanotubes is provided