Hybrid diffuse optical techniques for continuous hemodynamic measurement in gastrocnemius during plantar flexion exercise
Hybrid diffuse optical techniques for continuous hemodynamic measurement in gastrocnemius during plantar flexion exercise
复制标题
DOI：
10.1117/1.jbo.20.12.125006
复制
发表时间：
2015-12-01
影响因子：
3.5
通讯作者：
Yu, Guoqiang
中科院分区：
文献类型：
--
作者：
Henry, Brad;Zhao, Mingjun;Yu, Guoqiang
我们的实验室最近应用了闭塞校准和门控技术，用于在握力练习期间对前臂肌肉血流动力学进行连续和绝对的漫射光学测量。将这些技术从前臂转移到下肢是本研究的目标，因为各种疾病优先影响下肢肌肉。本研究采用混合近红外光谱和漫相关光谱系统与门控算法，连续量化的内侧腓肠肌在跖屈运动中的血流动力学反应在10名健康受试者。光学测量的结果包括氧合血红蛋白、脱氧血红蛋白和总血红蛋白浓度、血氧饱和度以及血流量（rBF）和耗氧率（rVO（2））的相对变化。我们分别用静脉和动脉闭塞获得的BF和VO2的绝对基线值校准rBF和rVO（2）曲线。这项调查的结果与类似研究的值相当。此外，显着的相关性，观察到之间的休息局部肌肉BF测量的光学技术和整个肢体BF测量同时应变计静脉体积描记术。运动过程中广泛的血液动力学和代谢特征将允许未来的比较研究，以调查混合技术在受疾病影响的肌肉中的诊断价值。(C)2015年，美国光电仪器工程师学会（SPIE）
Occlusion calibrations and gating techniques have been recently applied by our laboratory for continuous and absolute diffuse optical measurements of forearm muscle hemodynamics during handgrip exercises. The translation of these techniques from the forearm to the lower limb is the goal of this study as various diseases preferentially affect muscles in the lower extremity. This study adapted a hybrid near-infrared spectroscopy and diffuse correlation spectroscopy system with a gating algorithm to continuously quantify hemodynamic responses of medial gastrocnemius during plantar flexion exercises in 10 healthy subjects. The outcomes from optical measurement include oxy-, deoxy-, and total hemoglobin concentrations, blood oxygen saturation, and relative changes in blood flow (rBF) and oxygen consumption rate (rVO(2)). We calibrated rBF and rVO(2) profiles with absolute baseline values of BF and VO2 obtained by venous and arterial occlusions, respectively. Results from this investigation were comparable to values from similar studies. Additionally, significant correlation was observed between resting local muscle BF measured by the optical technique and whole limb BF measured concurrently by a strain gauge venous plethysmography. The extensive hemodynamic and metabolic profiles during exercise will allow for future comparison studies to investigate the diagnostic value of hybrid technologies in muscles affected by disease. (C) 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)