Development of Biomedical Polymer-Silicate Nanocomposites: A Materials Science Perspective
Development of Biomedical Polymer-Silicate Nanocomposites: A Materials Science Perspective
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DOI：
10.3390/ma3052986
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发表时间：
2010-04-28
期刊：
影响因子：
3.4
通讯作者：
Schmidt G
中科院分区：
文献类型：
--
作者：
Wu CJ;Gaharwar AK;Schexnailder PJ;Schmidt G
生物医用聚合物-硅酸盐纳米复合材料有可能成为生物医学应用发展的关键，从诊断和治疗设备、组织再生和药物输送基质到各种生物技术，这些生物技术受到生物学的启发，但只有间接的生物医学联系。对聚合物-纳米颗粒相互作用的基本了解对于控制材料的结构-性质关系是绝对必要的，这些材料需要在应用所要求的化学、物理和生物约束范围内工作。本文综述了聚合物-硅酸盐纳米复合材料(包括粘土基硅酸盐纳米颗粒和生物活性玻璃纳米颗粒)在生物医学领域应用的最新研究进展。突出了生物技术和生物医学纳米复合材料的新趋势，并对潜在的新应用领域进行了研究。
Biomedical polymer-silicate nanocomposites have potential to become critically important to the development of biomedical applications, ranging from diagnostic and therapeutic devices, tissue regeneration and drug delivery matrixes to various bio-technologies that are inspired by biology but have only indirect biomedical relation. The fundamental understanding of polymer-nanoparticle interactions is absolutely necessary to control structure-property relationships of materials that need to work within the chemical, physical and biological constraints required by an application. This review summarizes the most recent published strategies to design and develop polymer-silicate nanocomposites (including clay based silicate nanoparticles and bioactive glass nanoparticles) for a variety of biomedical applications. Emerging trends in bio-technological and biomedical nanocomposites are highlighted and potential new fields of applications are examined.