EEG arousals and awakenings in relation with periodic leg movements during sleep
EEG arousals and awakenings in relation with periodic leg movements during sleep
复制标题
睡眠期间周期性腿部运动与脑电图唤醒和觉醒的关系
DOI：
10.1046/j.1365-2869.2000.00202.x
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发表时间：
2000
影响因子：
4.4
通讯作者：
Billiard
中科院分区：
文献类型：
--
作者：
Karadeniz;Ondze;Besset;Billiard
众所周知，周期性的腿部运动经常伴随着完全觉醒或EEG觉醒的迹象。这些EEG觉醒与腿部运动的时间关系因患者而异。它们可以在腿部运动之前或之后发生，也可以同时发生。目前尚不清楚这些觉醒是否触发腿部运动，或者，是否EEG觉醒和腿部运动是一个共同的病理生理机制的单独表达。我们研究了10名周期性腿部运动患者的5种EEG觉醒（如α活动、K-复合体、纺锤波、K-α、K-纺锤波活动和觉醒）与腿部运动的时间关系。这些脑电图觉醒被认为是与腿部运动，如果他们发生10秒之前/之后或同时发生的右或左胫骨肌电图电位的发病。 结果发现，49.19%的脑电觉醒发生在腿运动之前，30.61%同时发生，23.18%发生在腿运动之后。在腿部运动前10秒的EEG唤醒次数显著高于同时或在10秒后。 阿尔法活动是最常见的现象与腿部运动，无论其时间组织，并显着较高的运动前10秒。 在腿部运动之前，纺锤体和K-纺锤体活动显著较高，而K-复合体活动在腿部运动期间显著更频繁。腿部运动后的觉醒次数显著高于同时运动。这些结果表明，腿部运动不是主要的，而是一种与潜在的唤醒障碍相关的现象。
It is known that periodic leg movements are frequently accompanied by full awakenings or by signs of EEG arousals. The time relationship of these EEG arousals with leg movements varies from patient to patient. They may precede or follow leg movements or occur simultaneously. It is not clear whether these arousals trigger leg movements or, alternatively, whether both EEG arousals and leg movements are separate expressions of a common pathophysiological mechanism. We investigated the temporal relationship of five EEG arousals, such as alpha activity, K‐complexes, spindles, K‐alpha, K‐spindle activities and awakenings, with leg movements in 10 periodic leg movement patients. These EEG arousals were considered to be associated with leg movements if they occurred 10 s before/after or simultaneously with the onset of right or left tibialis muscle EMG potentials. It was found that 49.19% of EEG arousals occurred before leg movements, 30.61% occurred simultaneously and 23.18% occurred just after leg movements. The number of EEG arousals was significantly higher in the 10 s preceding leg movement than simultaneously or in the 10 s following. Alpha activity was the phenomenon associated most frequently with leg movements, irrespective of its temporal organization and was significantly higher during the 10 s preceding movement. Spindle and K‐spindle activities were significantly higher before leg movement, whereas K‐complex activity was significantly more frequent during leg movements. The number of awakenings was significantly higher after leg movements than simultaneously. These results indicated that leg movements are not primary, but rather are a phenomenon associated with an underlying arousal disorder.