Decision Making and Response Inhibition as Predictors of Heavy Alcohol Use: A Prospective Study

Decision Making and Response Inhibition as Predictors of Heavy Alcohol Use: A Prospective Study
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DOI:
10.1111/j.1530-0277.2011.01437.x
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发表时间:
2011-06-01
影响因子:
3.2
通讯作者:
Sher, Kenneth J.
Sher, Kenneth J.
中科院分区:
医学3区
文献类型:
--
作者:
Goudriaan, Anna E.;Grekin, Emily R.;Sher, Kenneth J.

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背景:很少有研究调查"真实的世界"的前瞻性,预测价值的行为工具,用于实验室研究,以测试决策能力或冲动控制。目前的研究探讨在何种程度上2常用的决策/冲动控制措施前瞻性预测(重)酒精使用的样本中的大学students.Methods:200名健康的年轻人(50%的妇女)进行了爱荷华州赌博任务(IGT)和停止信号抑制任务,在大学的第二年。在测试,并在第四个大学学年结束时,重度酒精使用assessed.Results:不利的表现IGT与较高的分数在重度饮酒的措施和更高的数量/频率的酒精使用2年过去的神经认知测试的男性学生,即使在控制之前饮酒。这些结果针对神经认知测试前一段时间的大量饮酒和酒精使用进行了纠正。与性别的互动表明,这一一般模式适用于男生,但不适用于女生。反应抑制的水平是不相关的酒精使用的措施prospectively. Conclusion:这些研究结果表明,神经认知决策任务是预测适应不良的酒精使用。成功的决策者似乎表现出适应现实生活的决策,改变他们的饮酒习惯,以适应成年早期不断变化的挑战(例如,大学毕业),而不利的决策者不这样做,并继续大量饮酒。这些研究结果扩展了早期临床物质依赖组复发的神经认知预测因子的研究结果,亚临床酒精使用和滥用。
Background:Very few studies have investigated the "real world" prospective, predictive value of behavioral instruments used in laboratory studies to test decision-making abilities or impulse control. The current study examines the degree to which 2 commonly used decision-making/impulse control measures prospectively predict (heavy) alcohol use in a sample of college students.Methods:Two hundred healthy young adults (50% women) performed the Iowa Gambling Task (IGT) and a StopSignal inhibition task in the second college year. At testing and at the end of the fourth college year, heavy alcohol use was assessed.Results:Disadvantageous performance on the IGT was associated with higher scores on a heavy drinking measure and higher quantity/frequency of alcohol use 2 years past neurocognitive testing in male students even after controlling for prior drinking. These results were corrected for heavy drinking and alcohol use in the period before neurocognitive testing. Interactions with gender indicated that this general pattern held for male but not for female students. Level of response inhibition was not associated with either of the alcohol use measures prospectively.Conclusion:These findings indicate that a neurocognitive decision-making task is predictive of maladaptive alcohol use. Advantageous decision makers appear to show adaptive real-life decision making, changing their drinking habits to the changing challenges of early adulthood (e.g., finishing college), whereas disadvantageous decision makers do not, and continue to drink heavily. These findings extend earlier findings of neurocognitive predictors of relapse in clinical substance-dependent groups, to subclinical alcohol use and abuse.