Multicolour micropatterning of thin films of dry gels
Multicolour micropatterning of thin films of dry gels
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DOI：
10.1038/nmat1231
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发表时间：
2004-10-01
期刊：
影响因子：
41.2
通讯作者：
Grzybowski, BA
中科院分区：
文献类型：
--
作者：
Klajn, R;Fialkowski, M;Grzybowski, BA
在不同空间位置用多种化学品对表面进行微图案化通常需要多个冲压和配准步骤。在这里，我们描述了一种基于反应扩散现象的实验方法，该方法允许使用多种有色化学品同时对基板进行微图案化。在这种称为湿印（WETS）的方法中，两种或多种无机盐的水溶液被输送到由浅浮雕图案的琼脂糖印模制成的干离子掺杂明胶薄膜上。一旦形成保形接触，这些盐就会扩散到明胶中，在那里它们发生反应，产生深色沉淀物。表面平面内的颜色分离是扩散系数、溶解度积以及从印模释放的不同盐的量的差异的结果，并且通过基于反应扩散偏微分方程系统的理论模型忠实地再现。多色微图案可用作非二元光学元件，并有可能成为微分离和受控输送新应用的基础。
Micropatterning of surfaces with several chemicals at different spatial locations usually requires multiple stamping and registration steps. Here, we describe an experimental method based on reaction-diffusion phenomena that allows for simultaneous micropatterning of a substrate with several coloured chemicals. In this method, called wet stamping (WETS), aqueous solutions of two or more inorganic salts are delivered onto a film of dry, ionically doped gelatin from an agarose stamp patterned in bas relief. Once in conformal contact, these salts diffuse into the gelatin, where they react to give deeply coloured precipitates. Separation of colours in the plane of the surface is the consequence of the differences in the diffusion coefficients, the solubility products, and the amounts of different salts delivered from the stamp, and is faithfully reproduced by a theoretical model based on a system of reaction-diffusion partial differential equations. The multicolour micropatterns are useful as non-binary optical elements, and could potentially form the basis of new applications in microseparations and in controlled delivery.