Water-soluble nanoparticles from PEGylated linear cationic block copolymers and anionic surfactants
Water-soluble nanoparticles from PEGylated linear cationic block copolymers and anionic surfactants
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由聚乙二醇化线性阳离子嵌段共聚物和阴离子表面活性剂制成的水溶性纳米颗粒
DOI：
10.1007/s00396-017-4236-0
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发表时间：
2017
影响因子：
2.4
通讯作者：
Dibakar Dhara
中科院分区：
文献类型：
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作者：
S. Sahoo;Debabrata Dey;Dibakar Dhara
本研究通过研究不同时间尺度的微相行为，以了解内置超声透析过程（BUDP）期间玉米醇溶蛋白自组装的机制。结果表明，玉米醇溶蛋白溶液与透析液之间的相互传质改变了溶剂极性，引起玉米醇溶蛋白分子的构象转变，在超声场下形成稳定的液滴，并进一步固化致密的微球。研究了透析液性质对玉米醇溶蛋白自组装的影响。结果表明，pH和离子强度对所得玉米蛋白颗粒的尺寸、zeta电位和形貌有很大影响，其中在pH 4–pH 8和NaCl浓度≤ 10 mM时获得尺寸在1–2 μm左右、zeta电位> 30 mV的玉米蛋白微球。非离子Tween 60可以作为潜在的表面活性剂，通过物理结合提高玉米醇溶蛋白样品的稳定性。
The microphase behavior at different time scales was investigated to understand the mechanism of zein self-assembly during the built-in ultrasonic dialysis process (BUDP) in this study. The results indicated that the mutual mass transfer between zein solution and dialysate changed the solvent polarity, which caused the conformational transition of zein molecules, formation of stable droplets under the ultrasonic field, and further solidification of the compact microspheres. The effects of dialysate properties on zein self-assembly were investigated. The results showed that both pH and ionic strength had a great effect on the size, zeta potential, and morphology of the obtained zein particles, where zein microspheres with a size around 1–2 μm and zeta potential > 30 mV were obtained at pH 4–pH 8 and NaCl concentration ≤ 10 mM. And non-ionic Tween 60 could be used as a potential surfactant to improve the stability of zein samples through a physical combination.
胆汁盐与胆固醇部分修饰的两亲性聚磺酸盐的结合
DOI：
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发表时间：
--
期刊：
Polymer Journal (印刷中)
影响因子：
--
作者：
Shin-ichi Yusa
通讯作者：
Shin-ichi Yusa