Application of a channel biosensor for toxicity measurements in cultured Alexandrium tamarense.

Application of a channel biosensor for toxicity measurements in cultured Alexandrium tamarense.
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DOI:
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发表时间:
2000-11
期刊:
Journal of natural toxins
影响因子:
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通讯作者:
H. O. Lee;B. Cheun;J. Yoo;E. Watanabe;M. Han
H. O. Lee;B. Cheun;J. Yoo;E. Watanabe;M. Han
中科院分区:
其他
文献类型:
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作者:
H. O. Lee;B. Cheun;J. Yoo;E. Watanabe;M. Han

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本研究的目的是使用通道生物传感器检测塔玛亚历山大藻菌株的毒性。利用这种生物传感器,我们能够测量到单个浮游生物细胞中含有的非常少量的PSP毒素。然而,为了提高检测的灵敏度,测量至少100个细胞是更可取的。因此,在不久的将来,所提出的生物传感器系统可能用于监测少数天然有毒浮游植物产生的STX(萨克托毒素),也可以测量贝类中的少量毒素。
The purpose of this study is to examine the toxicity of Alexandrium tamarense strains using a channel biosensor. With this biosensor, we were able to measure very small quantities of PSP toxin contained within an individual plankton cell. However, measurement of at least 100 cells is more desirable for increasing the sensitivity of the assay. Therefore, in the near future, the proposed biosensor system may be used for monitoring the STX (saxitoxin) produced by a few naturally toxic phytoplankton, and also measuring small amounts of toxin in shellfish.